4'-Chloro-2'-Fluoroacetophenone
- CAS No.175711-83-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4'-Chloro-2'-Fluoroacetophenone (CAS 175711-83-8) designed for pharmaceutical synthesis. Reliable supply with strict quality control for global research and industrial applications.
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Product Overview
4'-Chloro-2'-Fluoroacetophenone is a highly specialized fluorinated organic compound that serves as a critical building block in modern pharmaceutical chemistry. Characterized by the presence of both chlorine and fluorine substituents on the aromatic ring, this ketone derivative offers unique reactivity profiles essential for the synthesis of complex therapeutic agents. Our facility produces this intermediate under stringent quality management systems to ensure consistency and reliability for downstream chemical processes.
The introduction of fluorine atoms into organic molecules is a strategic move in medicinal chemistry to enhance metabolic stability and bioavailability. As a trusted global manufacturer, we provide this material with exceptional purity levels, supporting research laboratories and production facilities in developing next-generation pharmaceutical products. Each batch undergoes rigorous analytical testing to confirm identity and potency before release.
Technical Specifications
We maintain tight control over physical and chemical parameters to meet the demanding standards of the fine chemical industry. The following table outlines the key specifications for our standard grade material.
| Parameter | Specification |
|---|---|
| Chemical Name | 4'-Chloro-2'-Fluoroacetophenone |
| CAS Number | 175711-83-8 |
| Molecular Formula | C8H6ClFO |
| Molecular Weight | 172.58 g/mol |
| Purity | ≥99.0% |
| Appearance | White crystalline powder |
| Boiling Point | 233°C |
| Density | 1.258 g/cm3 |
| Refractive Index | 1.512 |
Industrial Applications
This fluorinated acetophenone derivative is primarily utilized as a key intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its structural features allow for diverse functionalization reactions, including nucleophilic substitutions and condensation reactions. Common uses include the development of kinase inhibitors and other targeted therapies where specific halogen positioning is required for binding affinity.
- Pharmaceutical intermediate synthesis
- Organic chemistry research and development
- Custom synthesis projects for novel drug candidates
- Production of agrochemical precursors
Quality Assurance and Storage
Quality is paramount in our manufacturing process. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing the results of HPLC, NMR, and other relevant analytical methods. Our packaging ensures product integrity during transit, typically supplied in 25kg drums lined with protective materials to prevent moisture ingress.
For optimal stability, store this chemical in a tightly closed container within a cool, dry, and well-ventilated area. Keep away from incompatible substances such as strong oxidizing agents. Adherence to standard laboratory safety protocols and consultation of the Material Safety Data Sheet (MSDS) is recommended during handling. Contact our technical support team for bulk pricing information and logistical arrangements.
