Intermediates

4-Chloro-2-fluorobenzaldehyde

  • CAS No.61072-56-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Chloro-2-fluorobenzaldehyde (CAS 61072-56-8) serves as a critical building block for pharmaceutical and agrochemical synthesis, available in bulk quantities with certified quality.

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Product Technical Details

Product Overview

4-Chloro-2-fluorobenzaldehyde is a highly valued halogenated aromatic aldehyde utilized extensively in the fine chemical and pharmaceutical industries. As a versatile building block, this compound features a unique substitution pattern that enhances its reactivity in various organic transformations. The presence of both chlorine and fluorine atoms on the benzene ring provides distinct electronic properties, making it an ideal precursor for the synthesis of complex heterocycles and bioactive molecules.

Our manufacturing process ensures consistent quality and high purity levels suitable for demanding synthetic routes. We adhere to strict quality control protocols to guarantee that every batch meets international standards for industrial application. This chemical is particularly favored in medicinal chemistry for constructing fluorinated drug candidates, where metabolic stability and bioavailability are critical parameters.

Technical Specifications

ParameterSpecification
Chemical Name4-Chloro-2-fluorobenzaldehyde
CAS Number61072-56-8
Molecular FormulaC7H4ClFO
Molecular Weight158.56 g/mol
AppearanceOff-white crystalline powder
Purity (GC)≥99.0%
Moisture Content≤0.3%
Melting Point58-61°C
Boiling Point209.8°C
Density1.352 g/cm3

Industrial Applications

This fluorinated intermediate plays a pivotal role in the production of advanced pharmaceuticals and agrochemicals. Its primary use lies in the formation of carbon-carbon and carbon-heteroatom bonds through condensation reactions. Chemists utilize this aldehyde to introduce specific halogenated motifs into larger molecular structures, which is essential for optimizing the pharmacokinetic profiles of new drug entities.

  • Pharmaceutical Intermediates: Used in the synthesis of kinase inhibitors and anti-inflammatory agents.
  • Agrochemical Synthesis: Serves as a key component in developing novel herbicides and fungicides.
  • Material Science: Applied in the creation of liquid crystals and organic electronic materials.
  • Custom Organic Synthesis: Available for bespoke synthetic routes requiring high-purity starting materials.

Quality Assurance and Logistics

We understand the importance of reliability in the supply chain. Each production batch undergoes rigorous testing using gas chromatography and other analytical methods to verify purity and identity. A Certificate of Analysis (COA) is provided with every shipment to ensure transparency and compliance with your internal quality standards.

Regarding packaging, the product is securely packed in 25 kg drums to maintain integrity during transit. Custom packaging solutions are available upon request to suit specific logistical requirements. For storage, we recommend keeping the material in a cool, ventilated area away from direct sunlight and moisture to preserve its chemical stability over extended periods. Our global distribution network ensures timely delivery to partners worldwide, supporting continuous manufacturing operations without interruption.