Intermediates

4-Chloro-2-fluorobenzyl bromide

  • CAS No.71916-82-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Chloro-2-fluorobenzyl bromide (CAS 71916-82-0) designed for advanced organic synthesis. Reliable supply with ≥99.0% assay for pharmaceutical and chemical manufacturing.

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Product Technical Details

Product Overview

4-Chloro-2-fluorobenzyl bromide is a highly specialized fluorinated building block essential for modern organic synthesis and pharmaceutical development. As a key aryl halide intermediate, this compound offers exceptional reactivity due to the strategic positioning of chlorine and fluorine substituents on the benzyl ring. Our manufacturing process ensures consistent quality, making it an ideal choice for researchers and industrial chemists seeking reliable raw materials for complex molecular construction.

This chemical serves as a critical precursor in the production of various agrochemicals, pharmaceuticals, and advanced materials. The presence of the bromomethyl group facilitates nucleophilic substitution reactions, allowing for versatile downstream modifications. We prioritize strict quality control measures to guarantee that every batch meets international standards for purity and performance.

Technical Specifications

Our production facility utilizes advanced distillation and purification technologies to achieve high assay levels. The physical properties listed below are verified through rigorous analytical testing including Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC). Customers can request detailed Certificates of Analysis (COA) for every shipment to ensure compliance with their internal quality protocols.

ParameterValue
CAS Number71916-82-0
Molecular FormulaC7H5BrClF
Molecular Weight223.47 g/mol
AppearanceColorless to pale yellow transparent liquid
Assay≥99.0%
Density1.654 g/cm³
Boiling Point96ºC
Flash Point96-98ºC
Refractive Index1.5680

Industrial Applications

The versatility of 4-Chloro-2-fluorobenzyl bromide makes it indispensable across multiple chemical sectors. In pharmaceutical manufacturing, it is frequently employed in the synthesis of active pharmaceutical ingredients (APIs) where fluorinated motifs are required to enhance metabolic stability and bioavailability. The compound's reactivity allows for efficient coupling reactions, streamlining the production of complex therapeutic molecules.

Beyond pharmaceuticals, this intermediate is valuable in agrochemical formulation and material science. It acts as a foundational block for creating novel polymers and functional materials with specific electronic or physical properties. Our team supports clients in optimizing synthesis routes to maximize yield and minimize waste, aligning with green chemistry principles.

Quality Assurance and Logistics

We understand that supply chain reliability is crucial for continuous manufacturing operations. Our facility maintains substantial inventory levels to accommodate both sample requests and bulk orders. Each drum is sealed and labeled according to international hazardous material transport regulations to ensure safe delivery.

  • Strict quality control testing for every production batch
  • Flexible packaging options including 25 kg drums or custom requirements
  • Global shipping capabilities with documented safety data
  • Dedicated technical support for synthesis optimization

Storage recommendations include keeping the product in a cool, ventilated area away from direct sunlight and incompatible substances. Proper handling procedures involving personal protective equipment (PPE) are advised to maintain safety standards during laboratory or industrial use. Partner with us for a secure supply of high-performance chemical intermediates.