Intermediates

4-Chloro-2-(trifluoromethyl)benzonitrile

  • CAS No.320-41-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Chloro-2-(trifluoromethyl)benzonitrile (CAS 320-41-2) designed for advanced organic synthesis and pharmaceutical intermediates.

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Product Technical Details

Product Overview

4-Chloro-2-(trifluoromethyl)benzonitrile is a specialized fluorinated organic intermediate designed for high-performance chemical synthesis. As a key building block in the pharmaceutical and agrochemical industries, this compound offers exceptional reactivity and stability. Our manufacturing process ensures consistent quality, making it an ideal choice for complex molecular construction and research applications.

The presence of both chloro and trifluoromethyl groups on the benzene ring provides unique electronic properties, facilitating various nucleophilic substitution and cross-coupling reactions. This versatility allows chemists to develop novel active pharmaceutical ingredients and advanced crop protection agents with enhanced metabolic stability and bioavailability.

Technical Specifications

ParameterValue
CAS Number320-41-2
Molecular FormulaC8H3ClF3N
Molecular Weight205.564 g/mol
AppearanceLight brown to brown liquid
Assay≥98.0%
Density1.4±0.1 g/cm3
Boiling Point221.0±35.0 °C at 760 mmHg
Flash Point87.5±25.9 °C
Vapour Pressure0.1±0.4 mmHg at 25°C
Index of Refraction1.485

Industrial Applications

This fluorinated nitrile serves as a critical precursor in the production of heterocyclic compounds. Its primary applications include serving as a pharmaceutical intermediate used in the synthesis of kinase inhibitors and other therapeutic agents requiring fluorinated aromatic structures. It is also essential for developing herbicides and pesticides with improved environmental profiles.

In material science, this compound is utilized in the creation of high-performance polymers and liquid crystals. The trifluoromethyl group enhances lipophilicity and metabolic stability, which are crucial parameters in modern drug design. Our product supports diverse synthetic pathways including cyanation reactions and halogen exchange processes.

Quality Assurance and Storage

We adhere to strict quality control protocols. Each batch is accompanied by a Certificate of Analysis to verify purity and physical constants. To maintain integrity, store the product in a cool, ventilated area away from direct sunlight and incompatible materials. Proper handling ensures safety and optimal performance during downstream processing.

Our global supply chain guarantees timely delivery for bulk orders. Contact our technical team for customized packaging solutions and detailed safety data sheets. We are committed to providing reliable chemical solutions for industrial partners worldwide.