Intermediates

4-Chloro-3-fluoronitrobenzene

  • CAS No.350-31-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Chloro-3-fluoronitrobenzene (CAS 350-31-2) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical applications.

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Product Technical Details

Product Overview

4-Chloro-3-fluoronitrobenzene is a highly specialized fluorinated aromatic intermediate essential for modern organic synthesis pathways. This compound features a unique substitution pattern on the benzene ring, incorporating both chloro and fluoro groups alongside a nitro functionality. Such structural characteristics make it an invaluable building block for constructing complex molecular architectures required in the pharmaceutical and agrochemical industries.

Our manufacturing process ensures exceptional consistency and purity levels, meeting the rigorous demands of research and production environments. As a key precursor, this material facilitates the introduction of fluorine atoms into organic molecules, a strategy often employed to enhance metabolic stability and bioavailability in drug candidates.

Physical and Chemical Properties

The compound exhibits distinct physical properties that aid in its identification and handling during synthesis operations. It is characterized by a specific density and boiling point range, ensuring predictable behavior under various reaction conditions. The presence of the nitro group contributes to its reactivity, allowing for diverse chemical transformations such as reduction or nucleophilic substitution.

ParameterValue
Molecular FormulaC6H3ClFNO2
Molecular Weight175.545
Density1.5±0.1 g/cm3
Boiling Point240.1±20.0 °C at 760 mmHg
Melting Point61 °C
Flash Point99.0±21.8 °C
Assay≥98.0%

Industrial Applications

This fluorinated intermediate serves multiple critical roles across various chemical sectors. In pharmaceutical manufacturing, it acts as a precursor for developing novel therapeutic agents where fluorine substitution is crucial for optimizing pharmacokinetic profiles. Additionally, it finds utility in the synthesis of agrochemicals, contributing to the creation of advanced crop protection solutions.

  • Pharmaceutical intermediate synthesis
  • Agrochemical formulation development
  • Advanced organic research projects
  • Custom chemical manufacturing

Quality Assurance and Storage

We maintain strict quality control protocols throughout the production cycle. Each batch is accompanied by a Certificate of Analysis (COA) verifying purity and physical constants. To maintain stability, the product should be stored in a cool, ventilated environment away from direct sunlight and incompatible materials. Proper packaging ensures safety during global transportation.