4-Chloro-3-fluorophenylacetic acid
- CAS No.883500-51-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Chloro-3-fluorophenylacetic acid (CAS 883500-51-4), a key fluorinated aromatic intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
Request Bulk PricingProduct Technical Details
Product Overview
4-Chloro-3-fluorophenylacetic acid is a high-value fluorinated aromatic carboxylic acid widely employed as a critical building block in the synthesis of complex organic molecules. With its unique combination of chlorine and fluorine substituents on the phenyl ring, this compound offers enhanced metabolic stability and electronic tuning, making it particularly valuable in medicinal chemistry and agrochemical innovation.
Specifications
| Molecular Formula | C8H6ClFO2 |
|---|---|
| Molecular Weight | 188.583 g/mol |
| CAS Number | 883500-51-4 |
| Appearance | White to off-white powder |
| Assay | ≥98.0% |
| Melting Point | 88–91 °C |
| Density | 1.4 ± 0.1 g/cm³ |
| Boiling Point | 293.1 ± 25.0 °C at 760 mmHg |
| Flash Point | 131.1 ± 23.2 °C |
| Vapour Pressure | 0.0 ± 0.6 mmHg at 25 °C |
| Refractive Index | 1.548 |
Industrial Applications
This compound serves primarily as a specialty intermediate in multi-step organic syntheses. Its strategic halogen pattern enables selective cross-coupling reactions, nucleophilic substitutions, and derivatization pathways essential for constructing bioactive scaffolds. Key application sectors include:
- Pharmaceutical R&D: Precursor for novel CNS agents, anti-inflammatory leads, and targeted kinase inhibitors.
- Agrochemical Development: Building block for next-generation herbicides and fungicides requiring enhanced environmental persistence and selectivity.
- Advanced Materials: Used in the synthesis of liquid crystals and fluorinated polymers with tailored electronic properties.
Manufactured under stringent quality control protocols, our 4-Chloro-3-fluorophenylacetic acid meets global regulatory standards for research and industrial-scale production. Standard packaging is 25 kg per drum, with custom options available upon request. Store in a cool, dry, and well-ventilated area away from incompatible materials.
