4-Chloro-3-nitrobenzenesulfonamide
- CAS No.97-09-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 4-Chloro-3-nitrobenzenesulfonamide (CAS 97-09-6) for pharmaceutical synthesis. Ideal intermediate for Bcl-2 inhibitor research with reliable bulk supply.
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Product Overview
4-Chloro-3-nitrobenzenesulfonamide represents a critical specialized building block within the realm of advanced pharmaceutical chemistry. As a substituted benzenesulfonamide derivative, this compound features both chloro and nitro functional groups positioned strategically on the aromatic ring. These structural elements confer unique reactivity profiles, making the substance highly valuable for multi-step organic synthesis pathways. Our facility produces this material under strict quality control protocols to ensure consistency for downstream medicinal chemistry applications.
The molecular architecture of this sulfonamide allows for versatile transformations. The presence of the nitro group facilitates reduction reactions to form amines, while the chloro substituent enables nucleophilic aromatic substitution. This dual functionality positions the chemical as a pivotal precursor in the construction of complex heterocyclic systems often found in modern therapeutic agents. We prioritize molecular integrity to support rigorous research standards.
Technical Specifications
We adhere to rigorous analytical standards to guarantee the integrity of every batch produced. The following table outlines the key physicochemical properties and quality parameters associated with our standard production grade. Each certificate of analysis verifies these metrics against international benchmarks.
| Parameter | Value |
|---|---|
| CAS Number | 97-09-6 |
| Molecular Formula | C6H5ClN2O4S |
| Molecular Weight | 236.633 g/mol |
| Appearance | Light yellow to light brown crystalline powder |
| Assay | ≥98.0% |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 427.9±55.0 °C at 760 mmHg |
| Flash Point | 212.6±31.5 °C |
Industrial Applications
This compound serves primarily as a key intermediate in the development of small molecule inhibitors targeting the Bcl-2 protein family. The Bcl-2 pathway is a significant area of focus in oncology research, specifically regarding the regulation of apoptosis. By providing a high-purity starting material, we support research institutions and pharmaceutical companies in their pursuit of novel anti-apoptotic agents. The chemical stability and defined purity profile make it suitable for sensitive coupling reactions required in drug discovery pipelines.
Beyond oncology, sulfonamide derivatives often find utility in various biochemical assays and structure-activity relationship studies. Our clients utilize this material to explore new chemical spaces where the sulfonamide moiety contributes to binding affinity and metabolic stability. High purity is essential to avoid side reactions that could compromise experimental data during the synthesis of complex inhibitors.
Quality Assurance and Supply
- Consistent batch-to-batch reproducibility verified by HPLC and NMR spectroscopy.
- Comprehensive documentation including Certificate of Analysis (COA) and Method of Analysis (MOA).
- Flexible packaging options to suit laboratory scale or industrial production needs.
- Secure logistics ensuring product integrity during global transit and storage.
Proper storage is essential to maintain the specified quality attributes over time. We recommend keeping the material in a cool, ventilated environment away from direct sunlight and moisture to prevent degradation. Our packaging typically consists of 25 kg drums, though custom solutions are available upon request to align with specific supply chain requirements. As a global manufacturer, we are committed to providing reliable supply chains for essential pharmaceutical intermediates. Our team offers technical support to ensure the material integrates smoothly into your manufacturing process.
