Intermediates

4-Chloro-3-(trifluoromethyl)benzonitrile

  • CAS No.1735-54-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Chloro-3-(trifluoromethyl)benzonitrile designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical applications.

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Product Technical Details

Product Overview

4-Chloro-3-(trifluoromethyl)benzonitrile is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by the presence of both a chloro substituent and a trifluoromethyl group on the benzene ring, this molecule offers unique reactivity profiles that are essential for the development of complex pharmaceutical agents and agrochemical formulations. Our facility produces this intermediate under stringent quality management systems to ensure consistency and reliability for downstream processing.

The incorporation of fluorine atoms into organic molecules is a strategic approach in medicinal chemistry to enhance metabolic stability, lipophilicity, and bioavailability. As a key precursor, this benzonitrile derivative enables chemists to introduce these vital fluorinated motifs into larger molecular structures efficiently. We prioritize the delivery of materials that meet or exceed industry standards for purity and physical properties.

Key Specifications

Our manufacturing process is optimized to deliver product with high chemical integrity. The following table outlines the typical physical and chemical properties associated with this grade. Please note that specific batch data may vary slightly within acceptable tolerances, and a Certificate of Analysis is provided with every shipment.

ParameterSpecification
CAS Number1735-54-2
Molecular FormulaC8H3ClF3N
Molecular Weight205.564 g/mol
AppearanceOff-white crystalline powder
Assay (Purity)≥98.0%
Melting Point66-68°C
Boiling Point226.9±35.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point91.0±25.9 °C

Industrial Applications

This fluorinated nitrile is primarily utilized as an intermediate in the synthesis of high-value fine chemicals. Its structural features make it particularly suitable for nucleophilic substitution reactions and cross-coupling processes. The nitrile group can be further transformed into amines, acids, or tetrazoles, providing versatility in synthetic routes.

  • Pharmaceutical Intermediate: Used in the development of novel therapeutic compounds requiring fluorinated aromatic cores.
  • Agrochemical Synthesis: Serves as a precursor for herbicides and pesticides where metabolic stability is crucial.
  • Material Science: Applicable in the creation of specialized polymers and liquid crystal materials.
  • Research and Development: Essential reagent for academic and industrial laboratories focusing on organic methodology.
  • Custom Manufacturing: Available for tailored synthesis projects requiring specific purity profiles or packaging.

Quality Assurance and Storage

We understand that the quality of raw materials directly impacts the success of final products. Therefore, every batch of 4-Chloro-3-(trifluoromethyl)benzonitrile undergoes rigorous testing using advanced analytical techniques such as HPLC and GC-MS. Our quality assurance team ensures that all specifications are met before the product is released for shipment. Documentation including the Certificate of Analysis and Safety Data Sheet is readily available upon request.

Proper storage is essential to maintain the stability and integrity of this chemical. It should be stored in a cool, ventilated place away from direct sunlight and sources of ignition. Containers must be kept tightly closed when not in use to prevent moisture absorption or contamination. We recommend following all local safety regulations and handling guidelines during transportation and usage. For bulk orders or specific packaging requirements such as 25 kg drums or customized solutions, our logistics team is prepared to accommodate your needs efficiently.