4-Chloro-6,7-dimethoxyquinoline
- CAS No.35654-56-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Chloro-6,7-dimethoxyquinoline (CAS 35654-56-9) is a critical pharmaceutical intermediate for Cabozantinib synthesis. Available in bulk with strict quality control.
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Product Overview
4-Chloro-6,7-dimethoxyquinoline represents a highly specialized heterocyclic compound essential for modern medicinal chemistry applications. As a key building block, this quinoline derivative is meticulously synthesized to meet the rigorous demands of pharmaceutical research and development. Our facility ensures that every batch undergoes comprehensive analytical testing to guarantee structural integrity and chemical purity. The compound features a distinct chloro substitution pattern alongside dimethoxy groups, providing unique reactivity profiles suitable for complex organic transformations. We prioritize consistency and reliability, making this material an ideal choice for large-scale synthesis projects requiring precise molecular architecture.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 4-Chloro-6,7-dimethoxyquinoline |
| CAS Number | 35654-56-9 |
| Molecular Formula | C11H10ClNO2 |
| Molecular Weight | 223.66 g/mol |
| Purity (HPLC) | ≥98.0% |
| Appearance | Brownish gray solid |
| Boiling Point | 325.2 °C |
| Density | 1.265 g/cm3 |
| Flash Point | 80 °C |
Industrial Applications
This chemical serves as a pivotal intermediate in the synthesis of advanced kinase inhibitors, most notably contributing to the production of Cabozantinib. The quinoline scaffold is renowned for its biological activity, particularly in targeting specific enzymatic pathways involved in cellular regulation. Researchers utilize this compound to construct complex molecular frameworks required for next-generation therapeutics. Its high reactivity allows for versatile coupling reactions, facilitating the efficient assembly of target drug molecules. Furthermore, the stability of the dimethoxy groups ensures robust performance during multi-step synthesis routes. Our clients in the pharmaceutical sector rely on this material to accelerate their drug discovery pipelines while maintaining compliance with international quality standards.
Quality Assurance And Storage
We adhere to strict quality management protocols to ensure product safety and efficacy. Each production lot is accompanied by a Certificate of Analysis (COA) detailing comprehensive test results including HPLC purity, NMR spectral data, and residual solvent analysis. Proper storage is critical to maintain chemical stability over time. We recommend storing the material in a cool, ventilated environment away from direct sunlight and moisture sources. Packaging is designed to prevent contamination during transit, with options available for bulk drums or customized containers based on client requirements. Our logistics team ensures global shipping compliance, handling all necessary documentation for hazardous materials where applicable. By choosing our supply chain, partners gain access to reliable inventory levels and technical support for process optimization.
