4-Chloro-N-methylpyridine-2-carboxamide
- CAS No.220000-87-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Chloro-N-methylpyridine-2-carboxamide (CAS 220000-87-3) designed for pharmaceutical intermediate synthesis, ensuring consistent quality for API production.
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Product Overview
4-Chloro-N-methylpyridine-2-carboxamide is a specialized organic compound widely utilized in the pharmaceutical industry as a critical building block. With the CAS registry number 220000-87-3, this chemical serves as a key intermediate in the synthesis of advanced kinase inhibitors, including notable therapeutic agents like Sorafenib. Our facility ensures that every batch meets rigorous international standards, providing researchers and manufacturers with a reliable source for high-quality chemical materials.
As a dedicated manufacturer, we understand the importance of molecular integrity in drug development. This compound features a stable pyridine structure with specific chlorination and methylation patterns that facilitate efficient coupling reactions. Whether used for process development or large-scale API production, our material supports consistent reaction yields and purity profiles.
Technical Specifications
We maintain strict quality control protocols to guarantee the performance of 4-Chloro-N-methylpyridine-2-carboxamide. The following table outlines the typical physical and chemical properties observed in our standard production batches.
| Parameter | Specification |
|---|---|
| Chemical Name | 4-Chloro-N-methylpyridine-2-carboxamide |
| CAS Number | 220000-87-3 |
| Molecular Formula | C7H7ClN2O |
| Molecular Weight | 170.60 g/mol |
| Appearance | White to yellow crystalline powder |
| Purity (GC/HPLC) | ≥98.0% |
| Melting Point | 41-43°C |
| Loss on Drying | ≤1.0% |
| Packing | 25 kg/drum or customized |
Industrial Applications
The primary application of this intermediate lies in the pharmaceutical sector, specifically within the supply chain for oncology therapeutics. It acts as a precursor in multi-step synthesis routes requiring high regioselectivity. Beyond API manufacturing, it is also valuable in medicinal chemistry research for developing novel analogues and structure-activity relationship studies.
- Key intermediate for Sorafenib synthesis
- Building block for kinase inhibitor development
- Reagent for organic synthesis and R&D
- Compatible with various coupling reactions
Quality Assurance and Safety
Quality is the cornerstone of our manufacturing process. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results for identification, assay, impurities, and physical constants. We employ advanced analytical techniques such as HPLC and GC to verify purity levels exceeding 98.0%. Furthermore, our production facilities adhere to strict safety guidelines, ensuring hazardous materials are handled with care.
Regarding safety handling, this substance is classified under Hazard Class 8 with UN Number 1759. It should be stored in a cool, ventilated area away from incompatible substances. Proper personal protective equipment (PPE) is recommended during handling to prevent exposure. We offer global shipping solutions with compliant packaging to ensure safe delivery to your laboratory or production site.
Supply and Logistics
We are equipped to meet diverse demand scales, from kilogram-level research samples to ton-scale industrial orders. Our logistics network ensures timely delivery worldwide, with flexible packaging options available upon request. For clients requiring specific quality parameters or custom synthesis, our technical team is available to discuss tailored solutions that align with your project requirements.
