Intermediates

4-Chlorobenzoyl isothiocyanate

  • CAS No.16794-67-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Chlorobenzoyl isothiocyanate designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

4-Chlorobenzoyl isothiocyanate represents a highly versatile and essential chemical building block extensively utilized in modern organic synthesis laboratories and large-scale industrial manufacturing facilities. This specialized reagent features a reactive isothiocyanate functional group attached to a chlorinated benzoyl structure, enabling diverse and complex chemical transformations. Our facility produces this compound under strict quality control protocols to ensure consistent performance in downstream applications. As a leading global manufacturer, we prioritize exceptional purity and reliability to support complex synthetic routes required by the pharmaceutical and agrochemical sectors. The unique reactivity profile of this molecule makes it a preferred choice for chemists seeking efficient pathways to construct valuable heterocyclic systems.

Technical Specifications

The physical and chemical properties of this material are meticulously characterized to meet rigorous international standards. Each production batch undergoes comprehensive analytical testing to verify chemical identity, potency, and impurity profiles. The following table outlines the key parameters expected for premium grade material supplied by our advanced production lines. We maintain tight tolerances on all specifications to ensure reproducibility in your research and development processes.

ParameterValue
CAS Number16794-67-5
Molecular FormulaC8H4ClNOS
Molecular Weight197.64 g/mol
AppearanceLight yellow powder
Assay≥99.0%
Melting Point45 °C
Boiling Point300 °C
Density1.29 g/cm3
Flash Point135.2 °C

Industrial Applications

This compound serves as a critical intermediate in the preparation of various heterocyclic compounds and potential pharmaceutical agents. The high electrophilicity of the isothiocyanate moiety allows for efficient nucleophilic attack, facilitating the formation of thiourea derivatives which are prevalent in medicinal chemistry programs. Additionally, it is employed in the synthesis of specialized agrochemicals and functional polymers. Researchers value this reagent for its stability and predictable reaction kinetics during scale-up processes from bench to plant. The chloro substituent further provides a handle for subsequent cross-coupling reactions, expanding the synthetic utility significantly.

  • Synthesis of bioactive heterocycles and scaffolds
  • Production of thiourea-based enzyme inhibitors
  • Agrochemical intermediate manufacturing processes
  • Custom organic synthesis projects for niche markets
  • Development of novel functional materials

Quality Assurance and Safety

We implement a comprehensive quality management system to guarantee product integrity from raw material sourcing to final dispatch. Every shipment is accompanied by a detailed Certificate of Analysis confirming compliance with all specified parameters. Advanced testing methods including HPLC and NMR are utilized to validate structure and purity. Safety data sheets are provided to ensure proper handling within laboratory or plant environments. Our commitment to safety extends to packaging integrity and full regulatory documentation for global transport compliance.

Packaging and Storage

To maintain chemical stability over time, the product is packaged in secure, moisture-resistant drums suitable for long-term storage. We recommend keeping the material in a cool, ventilated area away from direct sunlight, moisture, and incompatible substances such as strong oxidizers. Custom packaging solutions are available to meet specific logistical requirements for international clients requiring bulk quantities. Proper storage conditions ensure the longevity and efficacy of the chemical properties throughout the supply chain lifecycle.