4-Chlorobutyronitrile
- CAS No.628-20-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 4-Chlorobutyronitrile liquid for pharmaceutical synthesis. Reliable supply with COA.
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Product Overview
4-Chlorobutyronitrile is a vital organic compound widely utilized in the pharmaceutical and fine chemical industries. Known chemically as γ-Chlorobutyronitrile, this substance serves as a critical building block for various synthetic pathways. Its unique structure, featuring both a nitrile group and a chloro substituent, makes it highly versatile for nucleophilic substitution reactions and cyclization processes. Our facility ensures that every batch meets rigorous international standards for purity and consistency.
As a leading global manufacturer, we understand the importance of supply chain reliability for complex pharmaceutical production. This intermediate is particularly valued for its role in the synthesis of active pharmaceutical ingredients (APIs), including anxiolytic medications. The stability and reactivity of this compound allow chemists to design efficient routes for creating heterocyclic structures essential in modern medicine.
Physical and Chemical Properties
Understanding the physicochemical profile of 4-Chlorobutyronitrile is essential for safe handling and process optimization. The compound exists as a colorless transparent liquid at standard temperature and pressure. It possesses a specific density that facilitates easy measurement and transfer in industrial settings. The boiling point indicates moderate volatility, requiring standard distillation equipment for purification. Additionally, the flash point suggests that while it is combustible, it can be managed safely with appropriate ventilation and fire safety protocols in place.
The molecular weight and formula provide key data for stoichiometric calculations during synthesis. Users should note the refractive index as a quality control parameter to verify identity and purity during incoming inspection. Proper storage in a cool, ventilated area is recommended to maintain stability over extended periods.
Quality Specifications
We adhere to strict quality assurance protocols to ensure that our 4-Chlorobutyronitrile exceeds industry expectations. Each production lot undergoes comprehensive testing using advanced chromatographic methods. The following table outlines the typical specifications for our commercial grade product:
| Parameter | Specification |
|---|---|
| Appearance | Colorless transparent liquid |
| Assay (GC) | ≥99.0% |
| Moisture Content | ≤0.2% |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 191.0±13.0 °C at 760 mmHg |
| Molecular Formula | C4H6ClN |
Industrial Applications
The primary application of this chemical lies in the pharmaceutical sector. It is a key intermediate in the manufacturing of Buspirone hydrochloride, a well-known therapeutic agent. Beyond this specific use, the compound is employed in the synthesis of various polymers and agrochemicals. Its ability to act as an electrophile in substitution reactions makes it indispensable for constructing carbon-nitrogen bonds. Research and development teams value this material for its consistent performance in scale-up processes.
Safety and Handling
Safety is our top priority. When handling 4-Chlorobutyronitrile, personnel should wear appropriate personal protective equipment, including chemical-resistant gloves and safety goggles. Operations should be conducted in a fume hood or well-ventilated area to prevent inhalation of vapors. In case of spillage, absorb with inert material and dispose of according to local environmental regulations. We provide comprehensive MSDS documentation with every shipment to ensure compliance with safety standards.
Packaging and Logistics
To ensure product integrity during transit, we package 4-Chlorobutyronitrile in robust 200 kg drums. Custom packaging solutions are available upon request to meet specific logistical requirements. Our global shipping network guarantees timely delivery to major chemical hubs worldwide. We support bulk orders and provide certificates of analysis (COA) with every shipment to verify quality upon arrival.
