Intermediates

4-Cyanobenzyl Bromide

  • CAS No.17201-43-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Cyanobenzyl Bromide intermediate essential for Alogliptin synthesis. Available in bulk with comprehensive quality documentation.

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Product Technical Details

Product Overview

4-Cyanobenzyl Bromide represents a critical building block in the realm of modern pharmaceutical synthesis. Identified by CAS number 17201-43-3, this organic compound serves as a vital precursor in the manufacturing of advanced therapeutic agents. Our facility specializes in the production of this high-grade chemical intermediate, ensuring that every batch meets stringent international quality standards required by the global pharmaceutical industry.

As a key component in the synthesis of DPP-4 inhibitors, specifically Alogliptin and its benzoate salt, this material plays an indispensable role in diabetes management medication production. We understand the critical nature of supply chain reliability for active pharmaceutical ingredient precursors. Therefore, our manufacturing processes are designed to maximize yield while maintaining exceptional purity levels suitable for sensitive downstream reactions.

Technical Specifications

Quality control is the cornerstone of our production philosophy. Each lot undergoes rigorous analytical testing to verify compliance with specified parameters. The following table outlines the standard technical specifications for our commercial grade 4-Cyanobenzyl Bromide:

ParameterSpecification
CAS Number17201-43-3
Molecular FormulaC8H6BrN
Molecular Weight196.04 g/mol
AppearanceOff-white crystalline powder
Purity≥99.0%
Loss on Drying≤0.5%
Melting Point115-117 °C
Boiling Point143 °C at 12mmHg
Density1.51 g/cm3

Industrial Applications

The primary application of this chemical lies within the pharmaceutical sector, specifically serving as an intermediate for the synthesis of Alogliptin. This compound facilitates the construction of complex molecular architectures required for effective enzyme inhibition. Beyond diabetes therapeutics, it finds utility in various organic synthesis pathways where a bromomethyl functional group attached to a benzonitrile core is required.

  • Essential intermediate for Alogliptin Benzoate production
  • Key reagent in heterocyclic compound synthesis
  • Utilized in medicinal chemistry research and development
  • Suitable for large-scale industrial manufacturing processes

Storage and Handling

Proper storage conditions are vital to maintain the stability and integrity of 4-Cyanobenzyl Bromide. The material should be kept in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Containers must remain tightly closed to prevent moisture absorption, which could compromise product quality. We recommend storing the product in its original packaging until ready for use.

Safety protocols must be strictly followed during handling. Personnel should wear appropriate personal protective equipment, including gloves and safety goggles. In case of spillage, standard chemical cleanup procedures should be enacted immediately. Our team provides comprehensive safety data sheets with every shipment to ensure compliance with local regulatory requirements.

Commitment to Quality

As a global manufacturer, we are dedicated to providing consistent quality and reliable supply. Every shipment is accompanied by a Certificate of Analysis (COA) verifying the physical and chemical properties. We offer flexible packing options, including 25kg cardboard drums, tailored to meet specific customer logistics requirements. Contact our sales team today for bulk pricing inquiries and technical support regarding your synthesis needs.