(4-Ethoxy-2,3-difluorophenyl)boronic acid
- CAS No.212386-71-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (4-Ethoxy-2,3-difluorophenyl)boronic acid designed for advanced Suzuki coupling reactions in pharmaceutical and OLED material synthesis.
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Product Overview
(4-Ethoxy-2,3-difluorophenyl)boronic acid represents a critical building block in modern organic synthesis, specifically tailored for cross-coupling reactions. This fluorinated aryl boronic acid derivative is engineered to meet the rigorous demands of medicinal chemistry and advanced material science. The presence of fluorine atoms at the 2 and 3 positions, combined with an ethoxy group at the 4 position, imparts unique electronic and steric properties that enhance reactivity in palladium-catalyzed transformations.
Our manufacturing process ensures exceptional batch-to-batch consistency, making this compound an ideal choice for researchers and industrial chemists focused on developing complex molecular architectures. The high purity profile minimizes side reactions, thereby improving overall yield and reducing downstream purification burdens in multi-step synthesis pathways.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 212386-71-5 |
| Molecular Formula | C8H9BF2O3 |
| Molecular Weight | 201.96 g/mol |
| Appearance | White powder |
| Assay (Purity) | ≥98.0% |
| Water Content | ≤0.50% |
| Melting Point | 151-154°C |
| Boiling Point | 315.98°C at 760 mmHg |
| Density | 1.299 g/cm3 |
| Refractive Index | 1.484 |
Industrial Applications
This specialized boronic acid finds extensive utility across several high-value sectors. In the pharmaceutical industry, it serves as a vital intermediate for constructing fluorinated drug candidates, where the introduction of fluorine often improves metabolic stability and bioavailability. The compound is particularly effective in Suzuki-Miyaura coupling reactions, enabling the formation of carbon-carbon bonds with high precision.
Beyond pharmaceuticals, this material is increasingly utilized in the production of organic light-emitting diode (OLED) materials. The specific substitution pattern supports the creation of emissive layers with optimized electronic properties, contributing to higher efficiency and longevity in display technologies. Fine chemical manufacturers also leverage this intermediate for the synthesis of agrochemicals and functional polymers requiring specific fluorinated motifs.
Quality Assurance and Packaging
We maintain strict quality control protocols throughout production. Each batch undergoes comprehensive analysis using HPLC and NMR spectroscopy to verify identity and purity levels. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with international standards.
- Standard packaging includes 25kg drums designed for safe transport.
- Custom packaging solutions are available upon request to suit specific logistical needs.
- Products are stored in cool, dry, and well-ventilated areas to maintain stability.
- Containers are kept tightly closed to prevent moisture absorption and contamination.
As a global manufacturer, we prioritize reliable supply chains and competitive bulk pricing structures. Our technical support team is available to assist with synthesis route optimization and application guidance, ensuring our partners achieve optimal results in their research and production endeavors.
