4-Fluoro-2-iodoaniline

Product Overview

4-Fluoro-2-iodoaniline is a highly specialized halogenated aromatic amine designed for rigorous applications in modern organic synthesis. As a critical building block, this compound features both fluorine and iodine substituents on the aniline ring, providing unique reactivity profiles for cross-coupling reactions. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for medicinal chemistry programs and process development scales.

We understand the demanding requirements of pharmaceutical and agrochemical research. Therefore, our production facilities adhere to strict quality management systems. Each lot undergoes comprehensive analytical testing to verify identity and purity. This commitment to quality allows researchers to rely on our materials for critical pathway development without the risk of impurity-related setbacks.

Technical Specifications

The following table outlines the key physical and chemical properties of our premium grade 4-Fluoro-2-iodoaniline. These parameters are verified using standard analytical methods including HPLC, NMR, and GC-MS.

Industrial Applications

This fluorinated iodinated aniline derivative serves as a versatile intermediate in the construction of complex molecular architectures. The presence of the iodine atom facilitates palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Buchwald-Hartwig, and Sonogashira couplings. Meanwhile, the fluorine substituent often enhances the metabolic stability and bioavailability of the final active pharmaceutical ingredient.

Common use cases include the synthesis of kinase inhibitors, receptor modulators, and other small molecule therapeutics. It is also utilized in the development of advanced agrochemicals and functional materials where specific electronic properties are required. Our technical team can provide guidance on optimal reaction conditions to maximize yield and minimize byproduct formation during your synthesis route.

Quality Assurance and Storage

We prioritize the stability and integrity of our chemical products. 4-Fluoro-2-iodoaniline should be stored in a cool, ventilated place away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent oxidation or degradation. We recommend storing the material under inert atmosphere conditions for long-term preservation.

Every shipment is accompanied by a Certificate of Analysis (COA) detailing the specific test results for that batch. Our logistics network ensures safe and compliant global delivery. For large-scale requirements, we offer flexible packaging solutions including 25 kg drums or custom configurations based on client needs. Contact our sales team for detailed safety data sheets and bulk pricing information.