Intermediates

4-Fluoro-2-methoxyaniline

  • CAS No.450-91-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Fluoro-2-methoxyaniline (CAS 450-91-9) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

4-Fluoro-2-methoxyaniline represents a critical fluorinated building block within the realm of advanced organic synthesis. Identified by CAS number 450-91-9, this compound serves as a versatile intermediate for the construction of complex molecular architectures. Our manufacturing process ensures high consistency and reliability, making it an ideal choice for research and industrial scale production. The presence of both fluoro and methoxy substituents on the aniline ring provides unique reactivity profiles, enabling diverse chemical transformations. We are committed to supplying this key chemical entity to partners who demand precision and quality in their synthetic workflows.

Chemical Characteristics and Physical Properties

This substance typically presents as a liquid ranging in color from yellow to light brown or faint red. Such physical characteristics are indicative of its chemical stability under standard storage conditions. The molecular formula C7H8FNO reflects a molecular weight of approximately 141.143 g/mol. Key physical parameters include a boiling point near 207.9 degrees Celsius and a density of 1.2 g/cm3. These properties are essential for process engineers when designing reaction vessels and distillation protocols. The flash point indicates standard safety precautions should be observed during handling and transportation. Understanding these physical constants is vital for safe integration into larger chemical processes.

Industrial Applications and Usage

Primarily utilized as a key intermediate in organic synthesis, this fluorinated aniline derivative finds extensive application in the development of pharmaceutical agents and agrochemical products. The fluorine atom often enhances metabolic stability and bioavailability in drug candidates, while the methoxy group offers sites for further functionalization. It is frequently employed in cross-coupling reactions, nucleophilic substitutions, and heterocycle formation. The electron-donating nature of the methoxy group combined with the electron-withdrawing fluorine atom creates a specific electronic environment on the aromatic ring. This facilitates selective reactions that are difficult to achieve with non-substituted anilines. Manufacturers seeking to optimize their synthesis routes will find this material provides a robust foundation for creating high-value downstream products. It is not intended for direct consumer use but rather as a reactant in controlled chemical environments. Research teams value this compound for its reliability in multi-step synthesis pathways.

Quality Assurance and Specifications

We adhere to strict quality control protocols to guarantee an assay purity of greater than 98.0 percent. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) to verify compliance with specified parameters. Our quality management system ensures that impurities are minimized, reducing the need for extensive downstream purification. This commitment to quality supports our clients in maintaining their own production standards and regulatory compliance. Consistency across batches is a priority, ensuring that your manufacturing processes remain stable and predictable over time. We utilize advanced analytical techniques to verify identity and purity before shipment.

ParameterSpecification
AppearanceYellow to light brown to faint red liquid
Assay≥98.0%
Molecular FormulaC7H8FNO
Molecular Weight141.143
Boiling Point207.9±20.0 °C at 760 mmHg
Density1.2±0.1 g/cm3

Packaging, Storage, and Safety

Standard packaging involves 200 kg drums, though we accommodate custom packaging requirements to suit specific logistical needs. Storage recommendations include keeping the container in a cool, ventilated place away from direct sunlight and incompatible materials. Proper ventilation is crucial to maintain safety standards within the warehouse facility. We recommend following all local regulations regarding the storage and transport of chemical intermediates. Our global supply chain capabilities ensure timely delivery to support your production schedules without interruption. Contact our technical team for detailed safety data sheets and handling guidelines to ensure operational safety.