Intermediates

4-Fluoro-2-(Trifluoromethyl)Benzoic Acid

  • CAS No.141179-72-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Fluoro-2-(Trifluoromethyl)Benzoic Acid (CAS 141179-72-8) designed for advanced organic synthesis. Reliable supply with ≥99.0% assay for pharmaceutical and agrochemical research.

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Product Technical Details

Product Overview

4-Fluoro-2-(Trifluoromethyl)Benzoic Acid is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. This highly functionalized benzoic acid derivative features both a fluoro substituent and a trifluoromethyl group on the benzene ring, providing unique electronic and steric properties that are highly valued in medicinal chemistry and material science applications.

The strategic placement of fluorine atoms enhances the metabolic stability and lipophilicity of downstream molecules, making this intermediate particularly useful in the development of novel pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality and high purity, meeting the rigorous demands of research laboratories and industrial production facilities alike.

Technical Specifications

ParameterValue
Chemical Name4-Fluoro-2-(Trifluoromethyl)Benzoic Acid
CAS Number141179-72-8
Molecular FormulaC8H4F4O2
Molecular Weight208.11 g/mol
AppearanceWhite crystalline powder
Assay≥99.0%
Moisture Content≤0.5%
Melting Point121-124°C
Density1.489 g/cm³

Industrial Applications

This fluorinated intermediate is primarily utilized in the synthesis of complex organic molecules where specific electronic modulation is required. The presence of the trifluoromethyl group significantly influences the reactivity of the carboxylic acid moiety, enabling diverse coupling reactions and functional group transformations.

  • Pharmaceutical Intermediates: Used in the synthesis of kinase inhibitors and receptor modulators where fluorine substitution improves bioavailability.
  • Agrochemical Synthesis: Serves as a precursor for herbicides and fungicides requiring enhanced environmental stability.
  • Material Science: Employed in the development of specialized polymers and liquid crystal materials.
  • Research and Development: Essential reagent for academic and industrial laboratories focusing on fluorine chemistry.

Quality Assurance and Logistics

We adhere to strict quality control protocols to ensure every batch meets specified purity standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing physical and chemical properties. Our facility is equipped to handle bulk orders efficiently, ensuring timely delivery for large-scale production needs.

Products are packaged in 25 kg drums or according to specific customer requirements to maintain integrity during transit. Proper storage in a cool, ventilated area is recommended to preserve stability. As a global manufacturer, we support international shipping and provide technical documentation to facilitate regulatory compliance in various regions.