Intermediates

4-Fluoro-3-methoxybenzonitrile

  • CAS No.243128-37-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Fluoro-3-methoxybenzonitrile (CAS 243128-37-2) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and chemical manufacturing.

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Product Technical Details

Product Overview

4-Fluoro-3-methoxybenzonitrile is a specialized fluorinated aromatic compound serving as a critical building block in modern organic synthesis. This chemical intermediate features a unique substitution pattern with both fluoro and methoxy groups on the benzene ring, enhancing its reactivity and versatility for downstream chemical transformations. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research laboratories and industrial production facilities focused on complex molecule assembly.

The presence of the nitrile group allows for various functional group interconversions, including hydrolysis to carboxylic acids or reduction to amines. Meanwhile, the fluorine atom provides metabolic stability and lipophilicity, which are valuable traits in medicinal chemistry and agrochemical development. We adhere to strict quality control protocols to guarantee that every batch meets the specified physical and chemical parameters required for sensitive synthetic routes.

Key Specifications

Quality and consistency are paramount in chemical manufacturing. The following table outlines the standard technical specifications for this product. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with these standards.

ParameterSpecification
Chemical Name4-Fluoro-3-methoxybenzonitrile
CAS Number243128-37-2
Molecular FormulaC8H6FNO
Molecular Weight151.138 g/mol
AppearanceWhite to off-white powder
Assay (Purity)≥98.0%
Moisture Content≤0.3%
Melting Point109 °C
Boiling Point234.3±25.0 °C at 760 mmHg
Density1.2±0.1 g/cm3

Industrial Applications

This fluorinated nitrile intermediate is primarily utilized in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Its structural properties make it suitable for nucleophilic aromatic substitution reactions and cross-coupling processes. In the pharmaceutical sector, it serves as a precursor for developing novel therapeutic agents where fluorine substitution is required to improve bioavailability and binding affinity.

Chemists value this compound for its stability under standard storage conditions and its predictable reactivity profile. Whether used in multi-step synthesis routes or as a key fragment in library generation for drug discovery, 4-Fluoro-3-methoxybenzonitrile provides a reliable foundation for innovation. Our global supply chain ensures that manufacturers can maintain continuous production schedules without interruption.

Storage and Handling

To maintain product integrity, proper storage conditions must be observed. The material should be kept in a cool, ventilated place away from direct sunlight and moisture sources. Containers must be tightly sealed when not in use to prevent contamination or degradation. Standard laboratory safety practices apply, including the use of appropriate personal protective equipment during handling.

We offer flexible packaging options, including 25 kg drums, to accommodate various production scales. Custom packaging is available upon request to meet specific logistical requirements. Our team provides comprehensive technical support to assist with integration into your existing manufacturing processes, ensuring safety and efficiency at every stage.