Intermediates

4-Fluoro-3-methylaniline

  • CAS No.452-69-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Fluoro-3-methylaniline (CAS 452-69-7) designed for pharmaceutical synthesis. Reliable supply with strict quality control and global logistics support.

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Product Technical Details

Product Overview

4-Fluoro-3-methylaniline is a specialized fluorinated aromatic amine that serves as a critical building block in modern organic synthesis and pharmaceutical manufacturing. As a key intermediate, this compound enables the construction of complex molecular architectures required for advanced therapeutic agents. Our facility produces this chemical under stringent quality management systems to ensure consistency and reliability for downstream processing.

The introduction of fluorine atoms into organic molecules often enhances metabolic stability and bioavailability, making this aniline derivative highly valuable in medicinal chemistry. We specialize in supplying bulk quantities to research institutions and industrial partners who demand exacting standards for their synthesis routes.

Technical Specifications

ParameterSpecification
Product Name4-Fluoro-3-methylaniline
CAS Number452-69-7
Molecular FormulaC7H8FN
Molecular Weight125.14 g/mol
AppearanceLight yellow transparent liquid
Purity≥98.0%
Water Content≤0.5%
Boiling Point85-86°C at 9mmHg
Melting Point35°C
Density1.12 g/cm3
Refractive Index1.5370

Industrial Applications

This fluorinated aniline is primarily utilized as a precursor in the synthesis of pharmaceuticals, agrochemicals, and functional materials. Its reactivity profile allows for diverse chemical transformations, including nucleophilic substitution and coupling reactions. Common uses include the development of kinase inhibitors and other small molecule drugs where fluorine substitution is critical for performance.

  • Essential intermediate for pharmaceutical drug discovery
  • Used in the production of advanced agrochemical agents
  • Suitable for custom organic synthesis projects
  • Compatible with various catalytic processes

Quality Assurance and Storage

Every batch undergoes rigorous analytical testing using HPLC and GC-MS to verify purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure compliance with your internal quality standards. Our logistics team ensures safe packaging in plastic drums or plastic-coated iron drums, typically 25kg per unit.

For optimal stability, store this product in a cool, dry, and well-ventilated area. Keep containers tightly closed when not in use to prevent moisture absorption or oxidation. While classified as non-dangerous goods for transport under standard conditions, always adhere to local safety regulations and handle with appropriate personal protective equipment. Our global supply chain capabilities ensure timely delivery to support your manufacturing schedules without interruption.