Intermediates

4-Fluoro-3-methylbenzoic Acid

  • CAS No.403-15-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Fluoro-3-methylbenzoic Acid (CAS 403-15-6) designed for advanced organic synthesis. Reliable supply with ≥99.0% purity for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

4-Fluoro-3-methylbenzoic Acid represents a critical fluorinated building block within the realm of fine chemical synthesis. As a specialized aromatic carboxylic acid derivative, this compound serves as an essential precursor for the development of complex pharmaceutical agents and agrochemical formulations. The strategic incorporation of fluorine atoms into organic structures is known to enhance metabolic stability and bioavailability, making this intermediate highly valuable for medicinal chemistry applications. Our manufacturing process ensures consistent quality and high purity levels to support rigorous research and production scales.

Technical Specifications

ParameterValue
Chemical Name4-Fluoro-3-methylbenzoic Acid
CAS Number403-15-6
Molecular FormulaC8H7FO2
Molecular Weight154.14 g/mol
Purity (HPLC)≥99.0%
AppearanceOff-white to white powder

Physical and Chemical Properties

This fluorinated benzoic acid derivative exhibits robust physical characteristics suitable for various reaction conditions. The compound presents as a crystalline powder with a defined melting point range between 164 and 168 degrees Celsius, indicating high structural integrity. With a boiling point of approximately 266.3 degrees Celsius and a flash point of 114.9 degrees Celsius, it maintains stability under standard processing temperatures. The density is recorded at 1.258 g/cm³, facilitating accurate dosing and formulation in synthetic pathways. These properties make it an ideal candidate for coupling reactions and functional group transformations.

Industrial Applications

  • Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and receptor modulators.
  • Agrochemical Development: Serves as a key building block for novel herbicide and pesticide structures.
  • Material Science: Applied in the creation of fluorinated polymers and liquid crystal materials.
  • Organic Synthesis: Utilized for cross-coupling reactions such as Suzuki or Buchwald-Hartwig protocols.

Quality Assurance and Packaging

We adhere to strict quality control protocols to ensure every batch meets international standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying purity and physical constants. The product is packaged in 25 kg drums to ensure safety during transit, though custom packaging solutions are available upon request to meet specific logistical requirements. Storage recommendations include keeping the material in a cool, ventilated environment away from incompatible substances. As a global manufacturer, we prioritize reliable supply chains and timely delivery to support your production schedules without interruption.