4-Fluoro-3-methylbenzonitrile
- CAS No.185147-08-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Fluoro-3-methylbenzonitrile (CAS 185147-08-4), a key fluorinated intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
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Product Overview
4-Fluoro-3-methylbenzonitrile is a high-value fluorinated aromatic nitrile widely employed as a critical building block in modern organic synthesis. With its unique combination of electron-withdrawing cyano and fluorine substituents alongside a methyl group, this compound serves as a versatile scaffold for constructing complex molecular architectures in medicinal chemistry and crop protection agent development.
Specifications
| Molecular Formula | C8H6FN |
|---|---|
| Molecular Weight | 135.14 g/mol |
| CAS Number | 185147-08-4 |
| Appearance | Gray solid |
| Purity | ≥99.0% |
| Melting Point | 53–56 °C |
| Boiling Point | 220.3 °C |
| Density | 1.11 g/cm³ |
| Refractive Index | 1.506 |
| Flash Point | 93.8 °C |
Industrial Applications
This fluorinated benzonitrile derivative functions primarily as a specialty intermediate in the synthesis of active pharmaceutical ingredients (APIs) and innovative agrochemical compounds. Its structural features enable selective functionalization through cross-coupling reactions, nucleophilic aromatic substitution, and heterocycle formation protocols.
- Serves as a precursor in the preparation of fluorinated heterocyclic systems prevalent in drug discovery pipelines
- Utilized in the development of novel crop protection agents requiring enhanced metabolic stability
- Compatible with standard industrial-scale synthetic methodologies under controlled conditions
For optimal stability and performance, store in a cool, dry, and well-ventilated area away from incompatible materials. Standard packaging is provided in 25 kg drums, with custom packaging options available upon request to meet specific logistical or regulatory requirements.
