Intermediates

4-Fluoro-3-methylphenol

  • CAS No.452-70-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Fluoro-3-methylphenol (CAS 452-70-0) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

4-Fluoro-3-methylphenol, identified by CAS number 452-70-0, stands as a critical fluorinated building block within the realm of modern organic chemistry. This specialized compound is engineered to meet the rigorous demands of industrial synthesis, offering exceptional stability and reactivity profiles. As a key intermediate, it facilitates the construction of complex molecular architectures required in various high-value sectors. Our manufacturing process ensures consistent quality, making it a preferred choice for research laboratories and large-scale production facilities alike.

The introduction of a fluorine atom into the phenolic structure significantly alters the electronic and steric properties of the molecule. This modification enhances metabolic stability and lipophilicity in downstream applications, which is particularly valuable in the development of advanced materials and fine chemicals. We prioritize safety and compliance throughout our supply chain, ensuring that every batch adheres to international standards for chemical handling and distribution.

Key Specifications

Quality assurance is paramount in our production workflow. Each lot undergoes stringent analytical testing to verify identity and purity. The physical characteristics are tightly controlled to ensure optimal performance during synthesis reactions. Below are the detailed technical parameters for this product:

ParameterSpecification
Chemical Name4-Fluoro-3-methylphenol
CAS Number452-70-0
Molecular FormulaC7H7FO
Molecular Weight126.128
AppearanceOff-white powder
Assay≥98.0%
Melting Point32 °C (lit.)
Boiling Point205.8±20.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point96.7±0.0 °C
Refractive Index1.520

Industrial Applications

This fluorinated phenol derivative serves as a versatile precursor in multiple chemical synthesis pathways. Its primary utility lies in the creation of specialized intermediates for the pharmaceutical and agrochemical industries. The unique reactivity of the hydroxyl group combined with the electron-withdrawing nature of the fluorine substituent allows for selective functionalization. This capability is essential for constructing biologically active molecules where precise structural alignment is required.

  • Utilized in the synthesis of complex organic frameworks for medicinal chemistry research.
  • Acts as a foundational building block for developing novel agrochemical agents.
  • Employed in the production of high-performance polymers and functional materials.
  • Supports custom synthesis projects requiring specific fluorinated aromatic structures.

Quality Assurance and Storage

We maintain a robust quality management system to guarantee product integrity from synthesis to delivery. Every shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. Proper storage is essential to maintain the chemical stability of 4-Fluoro-3-methylphenol. The material should be kept in a cool, ventilated environment away from direct sunlight and moisture. Packaging options include standard 25 kg drums, with flexibility to accommodate specific customer requirements for bulk orders. Our logistics team ensures safe and timely global delivery, adhering to all relevant transportation regulations for chemical goods.