4-Fluoro-3-methylpyridine
- CAS No.28489-28-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Fluoro-3-methylpyridine (CAS 28489-28-3) is a vital fluorinated building block for pharmaceutical synthesis. Available in bulk quantities with strict quality control.
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Product Overview
4-Fluoro-3-methylpyridine is a specialized fluorinated heterocyclic compound that serves as a critical building block in modern organic synthesis. As a key intermediate, this chemical facilitates the introduction of both fluoro and methyl functionalities into complex molecular structures. Our facility produces this compound under stringent quality management systems to ensure consistency and reliability for research and industrial applications.
The presence of the fluorine atom at the fourth position of the pyridine ring significantly alters the electronic properties of the molecule, enhancing its reactivity in nucleophilic substitution reactions. This makes it an invaluable asset for medicinal chemists aiming to optimize the metabolic stability and bioavailability of potential drug candidates. We supply this material to support diverse synthesis routes ranging from early-stage discovery to large-scale process development.
Key Specifications
Quality is paramount in chemical manufacturing. Each batch of 4-Fluoro-3-methylpyridine undergoes rigorous analytical testing to confirm identity and purity. The following table outlines the standard physical and chemical properties associated with this product.
| Parameter | Specification |
|---|---|
| CAS Number | 28489-28-3 |
| Molecular Formula | C6H6FN |
| Molecular Weight | 111.12 g/mol |
| Appearance | Yellow liquid |
| Purity | ≥98.0% |
| Density | 1.077 g/cm3 |
| Boiling Point | 145.4°C at 760 mmHg |
| Flash Point | 41.8°C |
Industrial Applications
This fluorinated pyridine derivative is extensively utilized in the pharmaceutical industry as a precursor for various therapeutic agents. Its structural motif is commonly found in kinase inhibitors and receptor modulators. Beyond human health, it also finds application in the synthesis of agrochemicals, where fluorine substitution often improves pesticidal activity and environmental persistence.
- Pharmaceutical intermediate for novel drug synthesis
- Building block for heterocyclic library construction
- Reagent in cross-coupling reactions
- Component in agrochemical formulation development
Storage and Handling
Proper storage is essential to maintain the integrity of 4-Fluoro-3-methylpyridine. The material should be kept in a tightly closed container within a cool, dry, and well-ventilated area. It is sensitive to moisture and light, so protection from these elements is recommended. Personnel handling this chemical must adhere to standard safety protocols, including the use of appropriate personal protective equipment such as gloves and safety goggles.
Supply and Quality Assurance
As a global manufacturer with two decades of experience, we offer competitive bulk pricing and reliable logistics solutions. Every shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified standards. Our technical support team is available to assist with customization requests and provide detailed safety data sheets. Partner with us for a secure supply chain of high-performance chemical intermediates.
