(4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acid
- CAS No.875446-29-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate for Anacetrapib synthesis. Reliable supply with COA.
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Product Overview
(4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acid is a specialized organoboron compound designed for advanced medicinal chemistry applications. As a key building block, this substance plays a critical role in the synthesis of complex pharmaceutical agents, particularly within the class of CETP inhibitors. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for research and development teams as well as large-scale production facilities.
We understand the stringent requirements of the pharmaceutical industry. Therefore, this boronic acid derivative is produced under strict quality control protocols to meet high purity standards. The compound features a unique substitution pattern that facilitates efficient cross-coupling reactions, such as Suzuki-Miyaura coupling, which are essential for constructing biaryl structures found in many modern therapeutics.
Technical Specifications
Our commitment to quality is reflected in the detailed physical and chemical properties of this material. Each batch undergoes rigorous analytical testing to verify identity and purity levels. The following table outlines the key specifications guaranteed for this product:
| Parameter | Value |
|---|---|
| CAS Number | 875446-29-0 |
| Molecular Formula | C10H14BFO3 |
| Molecular Weight | 212.03 g/mol |
| Appearance | White powder |
| Assay (Purity) | ≥98.0% |
| Water Content | ≤0.50% |
| Boiling Point | 324.0±52.0 °C at 760 mmHg |
| Flash Point | 149.8±30.7 °C |
Industrial Applications
This compound serves primarily as a vital intermediate in the manufacturing of Anacetrapib and related pharmacological candidates. Its structural properties allow for precise functionalization, enabling chemists to develop novel drug molecules with improved efficacy and safety profiles. Beyond its specific use in CETP inhibitor synthesis, this boronic acid is valuable for various organic synthesis pathways requiring robust aryl coupling partners.
Researchers utilize this material to explore new chemical spaces in drug discovery. The high purity level minimizes side reactions, ensuring cleaner reaction profiles and higher yields in downstream processes. Whether used in early-stage discovery or process chemistry optimization, this intermediate provides a reliable foundation for synthetic routes.
Quality Assurance and Safety
Safety and compliance are paramount in our operations. We provide comprehensive documentation, including Certificates of Analysis (COA), for every shipment. Our facilities adhere to international safety standards to ensure the material is handled and transported securely. Customers can rely on our technical support team for guidance on storage conditions and handling procedures to maintain product integrity.
Packaging and Storage
To preserve stability, the product is packaged in secure 25kg drums, with custom packaging options available upon request. It should be stored in a cool, dry, and well-ventilated area, keeping containers tightly closed to prevent moisture absorption. Proper storage ensures the material retains its specified properties over time, supporting your long-term production needs.
