4-Fluorobenzoic Acid
- CAS No.456-22-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Fluorobenzoic Acid (CAS 456-22-4), a key fluorinated aromatic intermediate for advanced organic synthesis in pharmaceutical and agrochemical manufacturing.
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Product Overview
4-Fluorobenzoic acid is a fluorinated aromatic carboxylic acid widely employed as a critical building block in the synthesis of complex organic molecules. With its well-defined reactivity and stability, this compound serves as a versatile intermediate in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers. Its para-fluoro substitution imparts unique electronic and steric properties that are leveraged in modern medicinal chemistry and materials science.
Specifications
| Molecular Formula | C7H5FO2 |
|---|---|
| Molecular Weight | 140.11 g/mol |
| CAS Number | 456-22-4 |
| Appearance | White to yellow powder |
| Purity (HPLC) | ≥99.0% |
| Moisture | ≤0.5% |
| Melting Point | 184 °C |
| Boiling Point | 253.7 °C |
| Density | 1.479 g/cm³ |
| Flash Point | 107.2 °C |
| Refractive Index | 1.537 |
Industrial Applications
As a high-value fluorinated intermediate, 4-fluorobenzoic acid is primarily utilized in multi-step synthetic routes requiring regioselective functionalization. Key application areas include:
- Pharmaceutical R&D: Precursor for fluorinated drug candidates targeting metabolic stability and enhanced bioavailability.
- Agrochemical Synthesis: Building block for herbicides and fungicides with improved environmental persistence profiles.
- Materials Chemistry: Monomer component in liquid crystals, OLED materials, and high-performance polymers.
- Chemical Research: Reference standard and derivatization agent in analytical and synthetic laboratories.
Stored in a cool, dry, and well-ventilated area, this product is typically supplied in 25 kg drums or customized packaging to meet global regulatory and logistical requirements. Our manufacturing process ensures consistent batch-to-batch quality, supported by comprehensive Certificates of Analysis (COA) and full regulatory documentation.
