4-Fluorobenzotrifluoride
- CAS No.402-44-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Fluorobenzotrifluoride (CAS 402-44-8) designed for pharmaceutical and agrochemical synthesis. Reliable bulk supply with comprehensive COA.
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Product Overview
4-Fluorobenzotrifluoride is a highly valued fluorinated aromatic compound extensively utilized in modern organic synthesis and industrial chemistry. As a key building block, it introduces both fluorine and trifluoromethyl functionalities into complex molecular structures. These specific modifications are critical for enhancing the metabolic stability, lipophilicity, and bioavailability of final pharmaceutical agents and agrochemical products. Our manufacturing process ensures exceptional consistency and purity, meeting the rigorous demands of global chemical supply chains and regulatory standards.
This compound serves as a versatile intermediate for multiple high-tech industries including medicinal chemistry and material science. The unique electronic properties provided by the fluorine atom combined with the steric influence of the trifluoromethyl group make it an indispensable reagent for researchers. We prioritize quality control at every stage, from raw material sourcing to final packaging, guaranteeing a product that performs reliably in sensitive reaction environments and large-scale production facilities.
Key Specifications
| Product Name | 4-Fluorobenzotrifluoride |
|---|---|
| CAS Number | 402-44-8 |
| Molecular Formula | C7H4F4 |
| Molecular Weight | 164.10 |
| Appearance | Clear colorless Liquid |
| Purity | ≥99.0% |
| Packing | 20kg/Carton or Customized |
Physical and Chemical Properties
The physical characteristics of 4-Fluorobenzotrifluoride are well-defined, facilitating its handling in various synthetic protocols. With a boiling point ranging between 102 and 105 degrees Celsius, it allows for efficient distillation and purification processes during downstream synthesis. The density of 1.293 g/cm3 indicates a relatively heavy liquid, which is typical for polyfluorinated aromatics and aids in phase separation during workup. Its refractive index of 1.401 further confirms the high quality and structural integrity of the batch produced in our facilities.
- High thermal stability suitable for demanding reaction conditions and elevated temperatures.
- Low melting point ensures liquid state at standard laboratory temperatures for easy dosing.
- Consistent flash point data supports safe storage and transportation protocols globally.
- Excellent solubility profile in common organic solvents used in pharmaceutical manufacturing.
Industrial Applications
The primary utility of this chemical lies in its role as a precursor for advanced materials and bioactive compounds. In the pharmaceutical sector, it is employed to synthesize novel drug candidates where fluorine substitution is known to improve pharmacokinetic profiles and binding affinity. Agrochemical manufacturers utilize this intermediate to develop robust pesticides and herbicides with enhanced environmental stability and efficacy against resistant strains. Additionally, the dye industry leverages its properties to create vibrant, long-lasting colorants for textiles and specialized coatings.
Our clients appreciate the reliability of our supply chain and technical expertise. Whether for large-scale industrial production or laboratory-scale research, we provide flexible packaging options including 20kg cartons or customized solutions based on specific project requirements. Technical support is available to assist with integration into your existing synthesis routes, ensuring optimal yield and safety during processing.
Storage and Handling
To maintain optimal quality, 4-Fluorobenzotrifluoride should be stored in closed containers at room temperature away from direct sunlight. The compound remains stable under normal storage and handling conditions when kept in a dry environment. However, standard safety precautions for organic solvents should be observed, including adequate ventilation and the use of appropriate personal protective equipment such as gloves and goggles. We provide comprehensive Certificates of Analysis (COA) with every shipment to verify compliance with specified parameters and international safety standards.
