4-Fluorobenzyl Bromide
- CAS No.459-46-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Fluorobenzyl Bromide (CAS 459-46-1) designed for advanced organic synthesis. Reliable supply with ≥99.0% GC purity for pharmaceutical and agrochemical intermediates.
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Product Overview
4-Fluorobenzyl Bromide is a premier halogenated aromatic compound extensively utilized in the field of modern organic chemistry. As a critical building block, this fluorinated reagent serves as a versatile alkylating agent for constructing complex molecular architectures. Our manufacturing process ensures exceptional consistency, making it an ideal choice for research laboratories and industrial-scale production facilities focused on high-value chemical synthesis.
The introduction of the fluorine atom enhances the metabolic stability and lipophilicity of downstream products, which is particularly valuable in the development of novel pharmaceutical agents and agrochemical formulations. We adhere to strict quality management systems to guarantee that every batch meets rigorous international standards for purity and performance.
Quality Specifications
Our commitment to excellence is reflected in our detailed specification sheet. Each production lot undergoes comprehensive analytical testing using gas chromatography and other advanced methodologies to verify composition and impurity profiles. The following table outlines the key physical and chemical parameters guaranteed for this product:
| Parameter | Specification |
|---|---|
| Chemical Name | 4-Fluorobenzyl Bromide |
| CAS Number | 459-46-1 |
| Molecular Formula | C7H6BrF |
| Molecular Weight | 189.03 g/mol |
| Appearance | Colourless to light yellow clear liquid |
| Purity (GC) | ≥99.0% |
| Density | 1.517 g/cm3 |
| Boiling Point | 85°C (refer to specific conditions) |
| Flash Point | 230°F |
| Refractive Index | 1.547 |
Industrial Applications
This compound functions primarily as a key intermediate in the synthesis of various fine chemicals. Its reactivity allows for efficient nucleophilic substitution reactions, facilitating the introduction of the 4-fluorobenzyl group into diverse molecular scaffolds. Common application areas include the production of pharmaceutical intermediates, where precision and purity are paramount for regulatory compliance.
Additionally, it is employed in the creation of agrochemical active ingredients and specialized material science projects. The high purity level ensures minimal side reactions, leading to improved yields and simplified downstream purification processes. Researchers value this reagent for its reliability in cross-coupling reactions and other transformation protocols essential for modern drug discovery pipelines.
Storage and Handling
To maintain optimal stability and safety, 4-Fluorobenzyl Bromide should be stored in a cool, ventilated warehouse away from direct sunlight and heat sources. Containers must be kept tightly closed when not in use to prevent moisture absorption and oxidation. Proper personal protective equipment, including gloves and eye protection, is recommended during handling to ensure personnel safety.
Packaging and Logistics
We offer flexible packaging solutions to meet the diverse needs of our global clientele. Standard packaging includes 200 kg drums, but we can also accommodate custom requirements based on specific project volumes. Our logistics network ensures timely delivery with full documentation, including Certificates of Analysis (COA) and Safety Data Sheets (SDS), supporting seamless integration into your supply chain.
