Intermediates

4-Fluoroindole

  • CAS No.387-43-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4-Fluoroindole (CAS 387-43-9) designed for advanced organic synthesis and pharmaceutical research applications with reliable global supply.

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Product Technical Details

Product Overview

4-Fluoroindole is a specialized heterocyclic organic compound that serves as a critical building block in modern medicinal chemistry and advanced material science. As a fluorinated derivative of the indole core structure, this chemical entity offers unique reactivity profiles that are highly valued in the development of novel pharmaceutical agents. Our facility produces this intermediate under strict quality control standards to ensure consistency and reliability for downstream synthesis processes.

The introduction of a fluorine atom at the fourth position of the indole ring significantly alters the electronic properties and metabolic stability of resulting molecules. This makes 4-Fluoroindole an essential precursor for researchers aiming to optimize drug candidates with improved bioavailability and binding affinity. We are committed to supplying this material to legitimate pharmaceutical companies and research institutions worldwide.

Technical Specifications

Quality assurance is paramount in the production of fine chemical intermediates. Each batch of 4-Fluoroindole undergoes rigorous analytical testing to verify compliance with specified parameters. The following table outlines the key physical and chemical properties associated with this product:

ParameterSpecification
CAS Number387-43-9
Molecular FormulaC8H6FN
Molecular Weight135.138 g/mol
AppearanceLight brown powder
Assay (Purity)≥98.0%
Melting Point30-32°C
Boiling Point258.0±13.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point109.9±19.8 °C

Industrial Applications

This fluorinated indole derivative is primarily utilized as an intermediate in the multi-step synthesis of complex organic molecules. Its applications span across various sectors including pharmaceutical drug discovery, agrochemical development, and functional material research. Chemists leverage the nucleophilic properties of the indole nitrogen and the electrophilic characteristics influenced by the fluorine substituent to construct diverse molecular architectures.

  • Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and central nervous system therapeutics.
  • Agrochemical Synthesis: Serves as a precursor for novel pesticides and herbicides requiring heterocyclic structures.
  • Material Science: Employed in the development of organic light-emitting diodes (OLEDs) and conductive polymers.
  • Research and Development: Essential for academic and industrial laboratories focusing on heterocyclic chemistry.

Quality Assurance and Packaging

We understand that the integrity of chemical supplies directly impacts the success of research and production timelines. Therefore, our manufacturing process adheres to international quality management systems. Every shipment is accompanied by a Certificate of Analysis (COA) detailing the specific test results for that batch. This transparency ensures that our clients can proceed with their synthesis routes with confidence.

Standard packaging consists of 25 kg drums, which are designed to protect the product from moisture and light during transit. However, we recognize that different projects have varying requirements. Consequently, we offer flexible packaging solutions tailored to customer specifications. Proper storage is essential to maintain product stability. The material should be kept in a cool, ventilated area away from incompatible substances. By choosing our supply chain, partners gain access to a reliable source of high-quality chemical intermediates supported by technical expertise and global logistics capabilities.