4-Fluoroindoline
- CAS No.552866-98-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Fluoroindoline (CAS 552866-98-5) designed for advanced organic synthesis and pharmaceutical research. Reliable supply with strict quality control.
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Product Overview
4-Fluoroindoline represents a critical heterocyclic building block within the realm of modern medicinal chemistry and organic synthesis. As a fluorinated derivative of indoline, this compound offers unique structural properties that enhance the metabolic stability and lipophilicity of downstream molecular structures. Our facility specializes in the production of high-quality chemical intermediates, ensuring that every batch of 4-Fluoroindoline meets rigorous international standards for purity and consistency.
The introduction of a fluorine atom at the fourth position of the indoline ring system significantly alters the electronic characteristics of the molecule. This modification is highly sought after in the development of novel pharmaceutical agents, agrochemicals, and advanced materials. Researchers utilize this intermediate to construct complex molecular architectures where precise spatial arrangement and electronic modulation are paramount for biological activity.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 4-Fluoroindoline |
| CAS Registry Number | 552866-98-5 |
| Molecular Formula | C8H8FN |
| Molecular Weight | 137.154 g/mol |
| Appearance | White to off-white solid |
| Purity (Assay) | ≥97.0% |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 215.7±29.0 °C at 760 mmHg |
| Flash Point | 84.2±24.3 °C |
| Refractive Index | 1.538 |
Industrial Applications
Primarily utilized as a key intermediate in organic synthesis, 4-Fluoroindoline serves as a foundational component for various chemical transformations. Its applications span across multiple sectors including pharmaceutical research, where it aids in the discovery of new therapeutic candidates. The compound is particularly valuable in the synthesis of kinase inhibitors and receptor modulators, where the indoline scaffold provides a rigid framework for ligand binding.
In addition to pharmaceutical uses, this chemical finds utility in the development of specialized materials and agrochemical formulations. The stability provided by the fluorine substitution makes it an excellent choice for processes requiring robust chemical performance under varying conditions. Our clients leverage this intermediate to accelerate their research and development cycles, benefiting from its reliable reactivity profile.
Quality Assurance and Handling
We maintain a comprehensive quality management system to ensure the integrity of our products. Each production lot undergoes strict analytical testing, including HPLC and NMR analysis, to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our manufacturing process adheres to safety and environmental regulations, ensuring sustainable production practices.
For optimal stability, 4-Fluoroindoline should be stored in a cool, ventilated place away from direct sunlight and moisture. The standard packaging consists of 25 kg drums, though we offer flexible packaging solutions tailored to specific customer requirements. Our logistics team ensures safe and timely global delivery, supporting your supply chain needs with efficiency and professionalism.
