Intermediates

4-Fluoropyridine

  • CAS No.694-52-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4-Fluoropyridine (CAS 694-52-0) is a vital fluorinated heterocyclic intermediate designed for pharmaceutical synthesis. Available in bulk quantities with strict quality control.

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Product Technical Details

Product Overview

4-Fluoropyridine is a highly valuable fluorinated heterocyclic compound that serves as a critical building block in modern organic synthesis and medicinal chemistry. As a key intermediate, this chemical facilitates the introduction of fluorine atoms into complex molecular structures, enhancing the metabolic stability and bioavailability of final pharmaceutical products. Our facility specializes in the production of high-grade 4-Fluoropyridine, ensuring consistent quality and reliability for downstream manufacturing processes.

This compound is characterized by its distinct chemical reactivity, making it an essential reagent for nucleophilic substitution reactions. The presence of the fluorine atom at the para position of the pyridine ring significantly alters the electronic properties of the molecule, allowing chemists to achieve specific synthetic outcomes that are difficult to accomplish with non-fluorinated analogs. We maintain rigorous production standards to deliver a product that meets the demanding specifications of the global pharmaceutical and agrochemical industries.

Technical Specifications

ParameterSpecification
Chemical Name4-Fluoropyridine
CAS Number694-52-0
Molecular FormulaC5H4FN
Molecular Weight97.09 g/mol
AppearanceYellow liquid
Purity≥98.0%
Boiling Point114.1°C at 760 mmHg
Density1.117 g/cm3
Flash Point22.8°C
Refractive Index1.473

Industrial Applications

The primary application of 4-Fluoropyridine lies in the synthesis of advanced pharmaceutical intermediates. It is extensively used in the development of novel drug candidates where fluorine substitution is required to optimize pharmacokinetic properties. Beyond pharmaceuticals, this chemical finds utility in the production of agrochemicals, liquid crystals, and specialized polymeric materials. Its versatility makes it a staple ingredient in research and development laboratories focused on heterocyclic chemistry.

Our clients utilize this intermediate for various coupling reactions and functional group transformations. The high purity level ensures minimal side reactions during synthesis, leading to higher yields and reduced purification costs. We support a wide range of scales, from gram-level research quantities to multi-ton industrial supply, accommodating the diverse needs of our global partner network.

Quality Assurance and Storage

Quality control is paramount in our manufacturing process. Every batch of 4-Fluoropyridine undergoes comprehensive testing using advanced analytical techniques such as Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR) to verify identity and purity. A Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We adhere to international safety and quality management systems to ensure product consistency.

For optimal stability, 4-Fluoropyridine should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is sensitive to moisture and light, so proper sealing is essential to maintain integrity over time. Our packaging options include secure drums designed to prevent leakage and contamination during transit. We recommend following standard safety protocols for handling fluorinated organic compounds, including the use of appropriate personal protective equipment.

Why Choose Our Supply

  • Consistent high purity levels exceeding 98 percent for reliable synthesis
  • Scalable production capacity to meet bulk industrial demands
  • Comprehensive technical support and documentation including COA
  • Competitive pricing structures for long-term partnership agreements
  • Global logistics network ensuring timely and secure delivery

We are committed to being your trusted partner in chemical sourcing. Our dedication to quality, safety, and customer service distinguishes us in the competitive landscape of fine chemical manufacturing. Contact our sales team today to discuss your specific requirements for 4-Fluoropyridine and discover how we can support your project goals with premium intermediates.