4-Glycidyloxycarbazole
- CAS No.51997-51-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Glycidyloxycarbazole (CAS 51997-51-4) serves as a critical pharmaceutical intermediate for Carvedilol synthesis, ensuring optimal reaction efficiency.
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Product Overview
4-Glycidyloxycarbazole is a highly specialized organic intermediate characterized by its unique epoxy-functionalized carbazole structure. This compound plays a pivotal role in the pharmaceutical industry, specifically serving as a critical building block in the synthesis of cardiovascular therapeutic agents. Our manufacturing process ensures exceptional chemical stability and reactivity, making it an ideal choice for complex organic synthesis pathways.
As a leading supplier, we understand the stringent requirements of pharmaceutical production. Therefore, our 4-Glycidyloxycarbazole is produced under strict quality control protocols to guarantee consistency across batches. The presence of the glycidyl ether group facilitates efficient nucleophilic substitution reactions, which are essential for constructing the molecular architecture of target active pharmaceutical ingredients.
Technical Specifications
| Parameter | Specification |
|---|---|
| Appearance | Pale yellow to almost white powder |
| Purity (HPLC) | ≥ 99.0% |
| Moisture Content | ≤ 0.5% |
| Total Impurities | ≤ 0.2% |
| Residue on Ignition | ≤ 0.1% |
Physical and Chemical Properties
| Molecular Formula | C15H13NO2 |
|---|---|
| Molecular Weight | 239.27 g/mol |
| Melting Point | 130-132 °C |
| Boiling Point | 464.9 °C at 760 mmHg |
| Density | 1.327 g/cm3 |
| Flash Point | 166.3 °C |
| Refractive Index | 1.729 |
Industrial Applications
This intermediate is primarily utilized in the manufacturing of Carvedilol and its phosphate salts. Carvedilol is a widely recognized medication used for managing hypertension and heart failure. The high purity of our 4-Glycidyloxycarbazole ensures minimal side reactions during the coupling steps, thereby improving the overall yield and quality of the final drug product.
- Essential precursor for Carvedilol synthesis.
- Suitable for large-scale pharmaceutical manufacturing.
- Compatible with various synthetic routes requiring epoxy functionality.
- Supports research and development of novel cardiovascular therapies.
Quality Assurance and Storage
We provide a comprehensive Certificate of Analysis (COA) with every shipment to verify compliance with specified parameters. To maintain integrity, the product should be stored in a cool, dry environment at -20°C. Containers must be well-closed to protect against moisture and strong light, preserving the reactivity of the epoxy group.
Our commitment to safety and regulatory compliance ensures that all materials are handled according to international chemical safety standards. Partner with us for reliable supply chains and technical support tailored to your synthesis needs. Packaging is available in 25kg cardboard drums or according to customer specified requirements.
