4-Hydroxy-3-Nitropyridine
- CAS No.5435-54-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Hydroxy-3-Nitropyridine (CAS 5435-54-1) designed for pharmaceutical intermediate synthesis. Available in bulk with strict quality control.
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Product Overview
4-Hydroxy-3-Nitropyridine is a specialized heterocyclic compound widely recognized for its utility in advanced organic synthesis and pharmaceutical development. As a key nitro-substituted pyridine derivative, this chemical serves as a critical building block for constructing complex molecular architectures. Our manufacturing process ensures exceptional consistency and purity, making it an ideal choice for research laboratories and industrial production facilities alike.
The compound features a unique electronic structure due to the presence of both hydroxyl and nitro functional groups on the pyridine ring. This configuration enhances its reactivity in nucleophilic substitution reactions and coupling processes. We prioritize stringent quality assurance protocols to guarantee that every batch meets the rigorous demands of modern medicinal chemistry and material science applications.
Key Specifications
Our production facility adheres to international quality standards to deliver products with reliable physical and chemical properties. The following table outlines the typical specifications for this grade. Custom specifications may be available upon request for specific project requirements.
| Parameter | Specification |
|---|---|
| CAS Number | 5435-54-1 |
| Molecular Formula | C5H4N2O3 |
| Molecular Weight | 140.097 g/mol |
| Appearance | Light yellow to yellow crystal |
| Purity (Assay) | ≥99.0% |
| Melting Point | 283-285 °C |
| Loss on Drying | ≤0.5% |
Industrial Applications
This pyridine derivative is primarily utilized as a versatile intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its chemical profile allows for diverse functionalization, enabling chemists to develop novel therapeutic candidates efficiently. Beyond pharmaceuticals, it finds application in the creation of agrochemicals and specialized fine chemicals where heterocyclic stability is required.
- Essential scaffold for drug discovery programs.
- Used in the preparation of kinase inhibitors and other targeted therapies.
- Suitable for cross-coupling reactions in organic synthesis.
- Supports the development of new materials with specific electronic properties.
Quality Assurance and Packaging
Quality is the cornerstone of our operation. Each production lot undergoes comprehensive analysis using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. A Certificate of Analysis (COA) is provided with every shipment to verify compliance with stated specifications. We maintain a robust supply chain to ensure timely delivery globally.
Standard packaging consists of 25kg drums, securely sealed to prevent moisture absorption and contamination. Custom packaging solutions are available to accommodate specific logistical needs. Proper handling procedures should be followed to maintain product integrity during transport and storage.
Storage and Safety
To preserve stability, store this material in a cool, dry, and well-ventilated area. Keep containers tightly closed when not in use to protect against humidity and light exposure. The compound should be handled in accordance with standard laboratory safety practices, including the use of appropriate personal protective equipment. Avoid contact with incompatible substances such as strong oxidizing agents.
