4-Hydroxybenzamide
- CAS No.619-57-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
4-Hydroxybenzamide (CAS 619-57-8) is a high-purity pharmaceutical intermediate primarily used in the synthesis of Febuxostat. Available in bulk quantities with strict quality control.
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Product Overview
4-Hydroxybenzamide is a critical organic compound widely recognized in the pharmaceutical and chemical industries for its versatility as a key building block. With the CAS registry number 619-57-8, this substance serves as an essential intermediate in the synthesis of various active pharmaceutical ingredients. Our manufacturing process ensures high purity levels, making it suitable for demanding synthetic routes where consistency and quality are paramount for downstream production.
As a leading manufacturer, we understand the importance of reliable supply chains in medicinal chemistry. 4-Hydroxybenzamide features a stable benzamide structure with a hydroxyl group at the para position, providing unique reactivity profiles for organic synthesis. This chemical is extensively utilized in the production of advanced therapeutics, including but not limited to gout management medications such as Febuxostat, ensuring patients receive effective treatments through robust supply networks.
Technical Specifications
| Parameter | Value |
|---|---|
| Product Name | 4-Hydroxybenzamide |
| CAS Number | 619-57-8 |
| Molecular Formula | C7H7NO2 |
| Molecular Weight | 137.136 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 161-162 °C |
| Boiling Point | 345.3±25.0 °C |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 162.6±23.2 °C |
Industrial Applications
The primary application of 4-Hydroxybenzamide lies in the pharmaceutical sector, specifically as a precursor in multi-step synthesis reactions. Its chemical structure allows for various functionalization processes, making it invaluable for research and development laboratories as well as large-scale production facilities. The compound is particularly noted for its role in the manufacturing of Febuxostat, a non-purine selective inhibitor of xanthine oxidase used in modern medicine.
Beyond pharmaceuticals, this intermediate finds utility in fine chemical synthesis where aromatic amides are required. Researchers value its consistent physical properties, such as a defined melting point and solubility characteristics, which facilitate predictable reaction outcomes. Our product supports innovation in drug discovery and process chemistry by providing a reliable foundation for complex molecular architectures.
Quality Assurance and Storage
Quality control is integral to our production workflow. Each batch of 4-Hydroxybenzamide undergoes rigorous testing using advanced analytical techniques to verify identity, purity, and physical constants. We provide a Certificate of Analysis (COA) with every shipment to ensure transparency and compliance with international standards. Our facility adheres to strict safety and environmental protocols during manufacturing to minimize risk.
For optimal stability, the product should be stored in a cool, ventilated area away from direct sunlight and moisture. Standard packaging includes 25 kg drums, though we offer flexible packaging solutions to meet specific customer logistics requirements. Proper handling ensures the material maintains its integrity throughout the supply chain, reducing waste and ensuring efficiency.
Safety and Handling
While 4-Hydroxybenzamide is a stable compound, standard laboratory safety practices should be observed during handling. Personnel are advised to use appropriate personal protective equipment, including gloves and eye protection, to prevent irritation. In case of spills, standard chemical cleanup procedures should be followed. We prioritize the safety of our clients and provide comprehensive safety data sheets upon request to ensure safe usage in your facility.
