Intermediates

4-Hydroxybenzylamine

  • CAS No.696-60-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Hydroxybenzylamine (CAS 696-60-6) is a critical pharmaceutical intermediate primarily used in the synthesis of prokinetic agents like Itopride.

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Product Technical Details

Product Overview

4-Hydroxybenzylamine, also known chemically as 4-(aminomethyl)phenol, represents a vital building block in the realm of organic synthesis and pharmaceutical manufacturing. With the CAS registry number 696-60-6, this compound is characterized by its distinct structural properties that make it indispensable for constructing complex molecular architectures. Our facility specializes in the production of this intermediate with a focus on consistent quality, high assay values, and reliability for large-scale industrial applications.

As a key precursor, this chemical plays a significant role in the development of active pharmaceutical ingredients (APIs). Specifically, it serves as an essential intermediate in the synthesis pathway of prokinetic agents, such as Itopride. The stability and purity of the starting material directly influence the efficiency and yield of downstream reactions, making the selection of a reputable supplier crucial for pharmaceutical manufacturers.

Technical Specifications

We adhere to strict quality control protocols to ensure every batch meets or exceeds industry standards. The following table outlines the typical physical and chemical properties of our premium grade 4-Hydroxybenzylamine.

ParameterSpecification
CAS Number696-60-6
Molecular FormulaC7H9NO
Molecular Weight123.152 g/mol
AppearanceBrown-yellow crystalline powder
Assay (Purity)≥98.0%
Melting Point116-118 °C
Boiling Point262.4±15.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point112.5±20.4 °C
Refractive Index1.594

Industrial Applications

The primary utility of 4-Hydroxybenzylamine lies within the pharmaceutical sector. Its chemical structure allows for versatile functionalization, making it a preferred choice for chemists designing synthesis routes for gastrointestinal therapeutics. Beyond its role in producing prokinetic drugs, this intermediate may also find applications in the development of other fine chemicals and specialized organic compounds where an aminomethyl phenol structure is required.

Our manufacturing process is optimized to minimize impurities that could interfere with subsequent catalytic steps. By maintaining an assay level of 98.0% or higher, we help our clients reduce waste and improve the overall economics of their production lines. We support various synthesis routes and can provide technical documentation to assist in process validation.

Quality Assurance and Packaging

Quality is the cornerstone of our operation. Each production batch undergoes rigorous testing using advanced analytical techniques such as HPLC and NMR to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Standard packaging is available in 25 kg drums, which are designed to protect the product from moisture and physical damage during transit. However, we understand that different facilities have different logistical needs. Therefore, we offer flexible packaging solutions according to customer requirements. Whether you need bulk shipments for large-scale manufacturing or smaller quantities for research and development, our logistics team ensures timely and secure delivery.

Storage and Handling

To maintain the integrity of 4-Hydroxybenzylamine, proper storage conditions are essential. The product should be stored in a cool, ventilated place away from direct sunlight and sources of ignition. Containers must be kept tightly closed when not in use to prevent exposure to atmospheric moisture, which could affect the physical appearance and chemical stability over time. Our team provides comprehensive safety data sheets (SDS) and handling guidelines to ensure safe usage within your facility.