4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one
- CAS No.91526-18-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used primarily in the synthesis of Azilsartan medoxomil. Available in bulk quantities with full documentation.
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Product Overview
4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one is a specialized organic compound designed for high-level pharmaceutical synthesis. This substance serves as a critical building block in the manufacturing of advanced antihypertensive medications. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream pharmaceutical applications. The compound is characterized by its stable cyclic carbonate structure, which facilitates efficient reaction pathways in complex organic synthesis.
We understand the stringent requirements of the global pharmaceutical supply chain. Therefore, every batch undergoes rigorous analytical testing to confirm identity and purity levels. This commitment to quality ensures that our clients receive materials that meet or exceed industry standards for active pharmaceutical ingredient synthesis. Our production capabilities allow us to support both research-scale requirements and large-scale commercial manufacturing needs.
Technical Specifications
The following table outlines the key physical and chemical properties of this product. These parameters are verified using standard analytical methods including HPLC, GC, and NMR spectroscopy.
| Parameter | Specification |
|---|---|
| CAS Number | 91526-18-0 |
| Molecular Formula | C5H6O4 |
| Molecular Weight | 130.099 g/mol |
| Appearance | White powder |
| Purity | ≥98% |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 213.8±32.0 °C at 760 mmHg |
| Flash Point | 92.8±18.6 °C |
| Refractive Index | 1.494 |
Industrial Applications
This compound is primarily utilized as a key intermediate in the synthesis of Azilsartan medoxomil, a widely prescribed angiotensin II receptor blocker. The high purity grade ensures minimal impurity carryover into the final drug substance, which is critical for regulatory compliance and patient safety. Beyond this specific application, the chemical structure offers versatility for researchers developing novel carbonate-based therapeutics or exploring new synthetic routes for cardiovascular medications.
Our technical team provides comprehensive support to optimize the integration of this material into your specific manufacturing process. We can assist with scale-up strategies and provide detailed documentation regarding the synthesis route and impurity profiles. This level of support helps streamline your development timeline and reduces potential risks associated with raw material variability.
Quality Assurance and Storage
To maintain product integrity, proper storage conditions are essential. The material should be kept in a cool and dry environment, ideally in a freezer at -20ºC. Containers must be well-closed to prevent exposure to moisture and strong light or heat sources. We package the product in 25kg cardboard drums, though custom packaging solutions are available upon request to suit specific logistical requirements.
Each shipment is accompanied by a Certificate of Analysis (COA) detailing the test results for that specific batch. Our quality management system ensures full traceability from raw material sourcing to final dispatch. We are committed to being a reliable global manufacturer, offering competitive bulk pricing and consistent supply continuity for long-term partners in the pharmaceutical industry.
