Intermediates

4-Hydroxyphenylboronic Acid

  • CAS No.71597-85-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Hydroxyphenylboronic Acid (CAS 71597-85-8) designed for efficient Suzuki coupling reactions. Ideal for pharmaceutical and OLED intermediate synthesis with reliable supply.

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Product Technical Details

Product Overview

4-Hydroxyphenylboronic Acid is a critical organoboron compound widely utilized in modern organic synthesis and medicinal chemistry. As a versatile building block, this chemical facilitates the construction of complex biaryl structures through palladium-catalyzed cross-coupling reactions. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for researchers and industrial producers focused on pharmaceutical intermediates and advanced material science.

The presence of the hydroxy group on the phenyl ring enhances its reactivity and solubility profiles, allowing for diverse functionalization strategies. We maintain strict quality control protocols throughout production to guarantee consistency across batches, supporting large-scale commercial applications as well as laboratory-scale research initiatives.

Technical Specifications

ParameterValue
CAS Number71597-85-8
Molecular FormulaC6H7BO3
Molecular Weight137.93 g/mol
AppearanceOff-white to light brown powder
Assay (Purity)≥98.0%
Water Content≤0.50%
Density1.32 g/cm3
Melting Point>230 °C
Boiling Point351.4 °C at 760 mmHg

Industrial Applications

This boronic acid derivative serves as a key reagent in Suzuki-Miyaura coupling reactions, which are fundamental in the synthesis of active pharmaceutical ingredients (APIs). Its stability and reactivity make it suitable for creating biphenyl structures found in numerous therapeutic compounds. Additionally, the compound is increasingly utilized in the production of organic light-emitting diode (OLED) materials, where precise chemical structures are required for optimal electronic performance.

Key application areas include:

  • Synthesis of pharmaceutical intermediates for drug discovery
  • Production of OLED materials and electronic chemicals
  • Development of agrochemical intermediates
  • Material science research and polymer modification

Quality Assurance and Packaging

We understand that consistency is vital for industrial processes. Every batch undergoes rigorous testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) to verify identity and purity. A Certificate of Analysis (COA) is provided with each shipment to ensure compliance with your internal quality standards.

Standard packaging includes 25kg drums, securely sealed to prevent moisture absorption and contamination. Custom packaging solutions are available upon request to meet specific logistical requirements. Proper storage in a cool, dry, and well-ventilated area ensures the long-term stability of the product.