4-Hydroxypyridine
- CAS No.626-64-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 4-Hydroxypyridine (CAS 626-64-2) designed for pharmaceutical synthesis. Ideal intermediate for Torasemide production with strict quality control.
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Product Overview
4-Hydroxypyridine is a critical heterocyclic compound widely utilized in the pharmaceutical and fine chemical industries. As a key building block, it serves as an essential intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Our manufacturing process ensures high chemical stability and consistency, making it a reliable choice for complex organic synthesis routes. The compound is characterized by its specific hydroxyl substitution on the pyridine ring, which facilitates diverse chemical transformations required in modern drug discovery and development.
We prioritize quality assurance at every stage of production. From raw material selection to final packaging, each batch undergoes rigorous testing to meet international standards. This commitment ensures that our clients receive materials that support efficient downstream processing without compromising on yield or purity. Whether used in laboratory research or large-scale industrial production, our 4-Hydroxypyridine provides the foundational quality necessary for successful outcomes.
Physical and Chemical Properties
Understanding the physical characteristics of this chemical is vital for safe handling and effective integration into synthesis protocols. The substance presents as a white to light yellow crystalline powder with a molecular formula of C5H5NO and a molecular weight of 95.09930. It exhibits a density of 1.111 g/cm3 and possesses a refractive index of 1.560. The boiling point is recorded at 230-235 °C at 12 mm Hg, while the melting point ranges between 150-151 °C. Safety parameters include a flash point of 221 °C, indicating standard handling precautions regarding heat sources are necessary during storage and transport.
Technical Specifications
The following table outlines the standard analytical specifications for our premium grade 4-Hydroxypyridine. These parameters are strictly controlled to ensure compatibility with sensitive synthetic applications.
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | White to light yellow crystalline powder | Conforms |
| Water | ≤1.0% | 0.31% |
| Single impurity | ≤0.5% | 0.08% |
| Total impurity | ≤2.0% | 0.13% |
| Assay | 98.0%~102.0% | 99.8% |
| Conclusion | Conforms to Factory Standard | |
Industrial Applications
This chemical intermediate is primarily employed in the manufacture of pharmaceutical agents, including but not limited to diuretic compounds such as Torasemide. Its high purity profile minimizes the formation of by-products during subsequent reaction steps, thereby optimizing overall process efficiency. Beyond pharmaceuticals, it finds utility in the development of agrochemicals and specialized organic materials where pyridine derivatives are required.
- Essential precursor for cardiovascular and diuretic medications.
- Compatible with various catalytic hydrogenation and substitution reactions.
- Suitable for scale-up from pilot plant to commercial manufacturing.
Quality Assurance and Storage
To maintain integrity, our products are packaged in secure 25kg cardboard drums or customized containers based on client requirements. Proper storage involves keeping the material in a cool, dry, and well-closed container, protected from moisture and strong light or heat sources. We provide comprehensive documentation, including Certificates of Analysis (COA), to verify compliance with specified parameters. Our global logistics network ensures timely delivery while maintaining product stability during transit. Partner with us for reliable supply chains and technical support tailored to your synthesis needs.
