Intermediates

4-Hydroxyquinoline

  • CAS No.611-36-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Hydroxyquinoline (CAS 611-36-9) designed for pharmaceutical synthesis and industrial applications. Reliable supply with comprehensive quality documentation.

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Product Technical Details

Product Overview

4-Hydroxyquinoline is a premier heterocyclic organic compound widely recognized for its critical role in advanced pharmaceutical synthesis. As a key hydroxylated quinoline derivative, this substance serves as an essential building block for the production of complex active pharmaceutical ingredients (APIs). Our manufacturing process ensures exceptional chemical stability and consistency, making it an ideal choice for research laboratories and industrial-scale production facilities alike. The compound is meticulously processed to meet stringent international quality standards, guaranteeing reliability for downstream synthetic applications.

In the realm of medicinal chemistry, this intermediate is particularly valued for its versatility. It functions effectively as a precursor in the synthesis of immunomodulators and other therapeutic agents. Beyond pharmaceutical uses, it exhibits notable properties in antimicrobial research and acts as a scavenger for photogenerated oxygen species, preventing photodegradation in sensitive formulations. Our commitment to quality ensures that every batch delivers the performance required for high-stakes chemical synthesis.

Technical Specifications

ParameterSpecificationTypical Result
AppearanceBuff to off-white powderOff-white powder
Purity (HPLC)≥98.5%98.98%
Melting Point199 ~206 °C202.5 ~205.3 °C
Moisture Content<0.5%0.18%
Assay (Titrimetry)≥98.0%98.7%
IR SpectrumConform to StandardConforms

Industrial Applications

The primary application of 4-Hydroxyquinoline lies in its capacity as a pharmaceutical intermediate. It is extensively utilized in the manufacturing route of Imiquimod, a significant therapeutic agent. The high purity levels we maintain are crucial for ensuring the safety and efficacy of the final API. Additionally, this chemical is employed in specialized research contexts where antimicrobial activity is being investigated. Its ability to inhibit the growth of specific intestinal bacteria makes it a valuable tool in microbiological studies.

Furthermore, the compound's chemical structure allows it to serve as a stabilizing agent in certain light-sensitive formulations. By acting as a sacrificial scavenger, it protects other components from oxidative damage during storage and processing. This multifunctionality expands its utility beyond simple synthesis, offering value in formulation development and stability testing protocols within the chemical industry.

Quality Assurance and Storage

Quality control is paramount in our production facility. Each batch undergoes rigorous testing using advanced analytical methods, including High-Performance Liquid Chromatography (HPLC), titrimetry, and infrared spectroscopy. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all test results against our factory standards. Our manufacturing processes adhere to strict safety and environmental guidelines, ensuring a sustainable supply chain.

  • Strict moisture control to maintain chemical stability.
  • Consistent particle size for improved solubility and reaction kinetics.
  • Full traceability from raw materials to finished goods.
  • Compliance with international shipping regulations for chemical safety.

For optimal preservation, 4-Hydroxyquinoline should be stored in a cool, ventilated warehouse away from direct sources of fire and heat. The storage temperature should not exceed 37 degrees Celsius to prevent degradation. We offer flexible packaging options, typically 25 kg per barrel, but can accommodate custom requirements based on specific logistical needs. Contact our technical sales team for detailed safety data sheets and bulk pricing information.