4-Iodo-2-(trifluoromethyl)benzonitrile
- CAS No.101066-87-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Iodo-2-(trifluoromethyl)benzonitrile (CAS 101066-87-9) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical research.
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Product Overview
4-Iodo-2-(trifluoromethyl)benzonitrile is a highly specialized fluorinated aromatic intermediate essential for modern organic synthesis. This compound features a unique structural combination of an iodine substituent and a trifluoromethyl group on a benzonitrile core, making it an invaluable building block for constructing complex molecular architectures. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications.
The presence of the iodine atom facilitates various cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings, while the trifluoromethyl group enhances metabolic stability and lipophilicity in final drug candidates. This dual functionality makes the compound a preferred choice for medicinal chemists developing new pharmaceutical agents and agrochemical solutions.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 101066-87-9 |
| Molecular Formula | C8H3F3IN |
| Molecular Weight | 297.016 g/mol |
| Appearance | Yellow powder |
| Assay | ≥98.0% |
| Melting Point | 50-55 °C |
| Boiling Point | 282.3±40.0 °C at 760 mmHg |
| Density | 2.0±0.1 g/cm3 |
Industrial Applications
This intermediate is primarily utilized in the synthesis of advanced pharmaceutical compounds and agrochemical active ingredients. The trifluoromethyl moiety is particularly sought after in drug design to improve bioavailability and binding affinity. Researchers leverage this building block to introduce fluorine atoms into lead compounds, optimizing their pharmacokinetic profiles.
- Pharmaceutical intermediate for kinase inhibitors and receptor modulators.
- Agrochemical synthesis for herbicides and fungicides.
- Material science applications requiring fluorinated aromatic structures.
- Custom organic synthesis for research and development projects.
Quality Assurance and Packaging
We adhere to strict quality control protocols to ensure every batch meets the specified purity standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results from HPLC, NMR, and other analytical methods. Our commitment to quality ensures reproducibility in your synthesis workflows.
Standard packaging consists of 25 kg drums, securely sealed to protect against moisture and contamination. Custom packaging solutions are available upon request to meet specific logistical requirements. We maintain a robust supply chain to guarantee timely delivery to global destinations.
Storage and Handling
To maintain stability, store this product in a cool, ventilated area away from direct sunlight and heat sources. Keep containers tightly closed when not in use. Proper handling procedures should be followed according to safety data sheets to ensure workplace safety and environmental compliance. Our team is available to provide technical support and safety documentation for all purchased materials.
