Intermediates

4-Iodophenol

  • CAS No.540-38-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Iodophenol intermediate suitable for OLED and pharmaceutical synthesis. Available in bulk with comprehensive quality documentation.

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Product Technical Details

Product Overview

4-Iodophenol, also known by its systematic name 4-Hydroxyiodobenzene, is a critical organic building block extensively utilized in modern chemical synthesis. As a halogenated phenol derivative, this compound serves as a versatile intermediate for constructing complex molecular architectures. Our facility produces this material under strict quality control protocols to ensure consistency across batches, making it an ideal choice for research and industrial scale applications.

The presence of the iodine substituent at the para position relative to the hydroxyl group enhances its reactivity in cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings. This specific reactivity profile makes it indispensable for medicinal chemists and material scientists aiming to introduce aromatic iodine motifs into their target molecules. We prioritize purity and stability to support downstream processes that demand high precision.

Key Specifications

Our manufacturing process is designed to meet rigorous international standards. Each batch undergoes comprehensive analytical testing to verify compliance with the specified parameters. The following table outlines the typical physical and chemical properties of our premium grade 4-Iodophenol.

ParameterSpecification
CAS Number540-38-5
Molecular FormulaC6H5IO
Molecular Weight220.01 g/mol
AppearanceWhite to light yellow crystalline powder
Purity>99.5%
Melting Point92-94 °C
Boiling Point138 °C at 5 mm Hg
Refractive Index1.669

Industrial Applications

This compound finds significant utility in multiple high-tech sectors. In the pharmaceutical industry, it acts as a key precursor for synthesizing active pharmaceutical ingredients (APIs). Its ability to participate in palladium-catalyzed reactions allows for the efficient formation of carbon-carbon and carbon-heteroatom bonds, which are fundamental steps in drug discovery pipelines.

Furthermore, in the field of organic electronics, 4-Iodophenol is employed as an intermediate in the production of OLED materials. The electronic properties conferred by the iodine atom are crucial for tuning the energy levels of emissive layers, contributing to the efficiency and longevity of display technologies. Our product supports the development of next-generation screens and lighting solutions.

Storage and Handling

To maintain the integrity of the chemical, proper storage conditions are essential. The product should be kept in a cool, dry, and well-ventilated warehouse environment. It is imperative to protect the packaging from direct sunlight and sources of ignition, as the material may be sensitive to heat and light exposure over extended periods.

Containers must remain sealed when not in use to prevent moisture absorption and contamination. For safety compliance, store this substance separately from strong acids and edible chemicals. Personnel handling this material should utilize appropriate personal protective equipment, including gloves and safety goggles, to minimize exposure risks during transfer and weighing operations.

Quality Assurance and Supply

We are committed to delivering consistent quality with every shipment. Our quality assurance team provides a Certificate of Analysis (COA) for each batch, detailing the test results against our internal specifications. As a global manufacturer, we offer flexible packaging options, including standard 25kg cardboard drums, and can accommodate custom requirements based on client logistics needs. Contact our sales team for current bulk pricing and technical support regarding your specific synthesis routes.