Intermediates

4-Isopropoxyphenylboronic acid

  • CAS No.153624-46-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Isopropoxyphenylboronic acid (CAS 153624-46-5) designed for pharmaceutical synthesis. Ideal for COX-2 inhibitor development and advanced organic coupling reactions.

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Product Technical Details

Product Overview

4-Isopropoxyphenylboronic acid represents a critical building block in modern organic synthesis, specifically designed for complex pharmaceutical applications. This boronic acid derivative, identified by CAS number 153624-46-5, serves as a versatile reagent for constructing sophisticated molecular architectures. Our facility produces this compound under strict quality control measures to ensure consistent performance in downstream reactions. The chemical structure features an isopropoxy group attached to the phenyl ring, enhancing its solubility and reactivity profiles in various catalytic cycles.

Technical Specifications

We maintain rigorous standards for all chemical outputs to meet international pharmaceutical grade requirements. The following table outlines the key physical and chemical properties verified during our comprehensive quality assurance process. Each batch is tested to ensure compliance with the specified parameters.

ParameterSpecification
Product Name4-Isopropoxyphenylboronic acid
CAS Number153624-46-5
Molecular FormulaC9H13BO3
Molecular Weight180.01 g/mol
AppearanceWhite or off-white solid powder
Assay≥98.0%
Water Content≤0.50%
Melting Point150-154°C
Density1.1 g/cm3

Industrial Applications

This compound is primarily utilized as a pharmaceutical intermediate in the development of advanced therapeutic agents. It plays a significant role in the synthesis of potent cytotoxic analogues related to marine alkaloids such as Lamellarin D. Furthermore, it is employed in the creation of cyclooxygenase-2 (COX-2) inhibitors, highlighting its importance in anti-inflammatory drug discovery programs. The chemical structure facilitates efficient Suzuki-Miyaura cross-coupling reactions, allowing medicinal chemists to introduce specific functional groups with high precision. Its stability under standard reaction conditions makes it a preferred choice for process chemistry teams.

Quality Assurance and Advantages

Our manufacturing process prioritizes high purity and stability to support research and production needs. We implement multiple purification steps to remove residual solvents and by-products. Key advantages of sourcing from our facility include:

  • Assay greater than 98 percent ensures minimal impurities for sensitive reactions.
  • Consistent batch-to-batch reproducibility supported by robust QC protocols.
  • Comprehensive documentation including Certificate of Analysis (COA) and Method of Analysis.
  • Technical support available for scale-up and process optimization inquiries.

Storage and Handling

To preserve chemical integrity, store this material in a cool, dry, and well-ventilated place. Keep containers tightly closed when not in use to prevent moisture absorption, which can affect boronic acid stability. The product should be protected from direct sunlight and sources of ignition. We offer flexible packaging options, including 25kg drums, which can be customized according to specific customer requirements. Global shipping is available with appropriate hazard classification documentation to ensure safe transport.