4-Methoxy-2-oxo-1H-pyridine-3-carbonitrile
- CAS No.21642-98-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-methoxy-2-oxo-1H-pyridine-3-carbonitrile (CAS 21642-98-8), a key heterocyclic intermediate for advanced pharmaceutical synthesis.
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Product Overview
4-Methoxy-2-oxo-1H-pyridine-3-carbonitrile (CAS 21642-98-8) is a high-value heterocyclic organic compound widely employed as a critical building block in the synthesis of complex pharmaceutical active ingredients. This molecule features a functionalized pyridone core with both nitrile and methoxy substituents, enabling diverse reactivity in multi-step synthetic sequences. Its structural versatility makes it particularly valuable in medicinal chemistry campaigns targeting kinase inhibitors, anti-inflammatory agents, and other bioactive small molecules.
Specifications
| Molecular Formula | C7H6N2O2 |
|---|---|
| Molecular Weight | 150.14 g/mol |
| CAS Number | 21642-98-8 |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98% |
| Storage | Store in a cool, dry place under inert atmosphere |
Industrial Applications
As a specialized intermediate, 4-methoxy-2-oxo-1H-pyridine-3-carbonitrile serves primarily in the research and development phase of drug discovery and scale-up manufacturing. Its applications include:
- Construction of fused pyridine derivatives for oncology and CNS therapeutic programs
- Synthesis of novel heterocyclic scaffolds via nucleophilic substitution or transition-metal-catalyzed coupling
- Use as a precursor in the preparation of functionalized quinolones and related pharmacophores
Our product is manufactured under stringent quality control protocols compliant with ICH guidelines, ensuring batch-to-batch consistency and suitability for GMP-relevant processes. Certificates of Analysis (COA), spectral data, and regulatory documentation are available upon request to support seamless integration into your synthetic workflow.
