4-Methoxyphenylacetic Acid
- CAS No.104-01-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Methoxyphenylacetic Acid (CAS 104-01-8), a key pharmaceutical intermediate used in the synthesis of active ingredients such as dextromethorphan.
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Product Overview
4-Methoxyphenylacetic Acid, also known as Homoanisic Acid or 2-(4-Methoxyphenyl)acetic Acid, is a high-value aromatic carboxylic acid widely employed as a critical building block in pharmaceutical synthesis. With a CAS number of 104-01-8 and molecular formula C9H10O3, this compound serves as an essential intermediate in the production of centrally acting antitussive agents, including dextromethorphan (CAS 125-71-3). Our product is manufactured under stringent quality control protocols to ensure consistent performance and regulatory compliance for global B2B customers.
Specifications
| Molecular Formula | C9H10O3 |
|---|---|
| Molecular Weight | 166.174 g/mol |
| Melting Point | 84–86 °C (lit.) |
| Boiling Point | 306.0 ± 17.0 °C at 760 mmHg |
| Density | 1.2 ± 0.1 g/cm³ |
| Flash Point | 124.3 ± 14.4 °C |
| Vapour Pressure | 0.0 ± 0.7 mmHg at 25 °C |
| Refractive Index | 1.538 |
| Appearance | White to off-white crystalline powder |
| Assay (Purity) | ≥98.0% |
Industrial Applications
As a versatile aromatic intermediate, 4-Methoxyphenylacetic Acid plays a pivotal role in multi-step organic syntheses within the pharmaceutical industry. Its primary application lies in the construction of morphinan-based scaffolds used in cough suppressants and other neurological therapeutics. Key advantages include:
- High reactivity in Friedel-Crafts acylation and alkylation reactions
- Excellent solubility profile for diverse solvent systems
- Consistent batch-to-batch quality suitable for GMP environments
- Scalable supply chain with flexible packaging options
Stored in a cool, well-ventilated area, the compound maintains stability under standard industrial handling conditions. Standard packaging is 25 kg per drum, with custom configurations available upon request to meet specific logistical or regulatory requirements.
