Intermediates

4-Methyl-3-nitro-1H-pyridin-2-one

  • CAS No.21901-18-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Methyl-3-nitro-1H-pyridin-2-one intermediate for advanced organic synthesis. Available in bulk with reliable quality assurance.

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Product Technical Details

Product Overview

4-Methyl-3-nitro-1H-pyridin-2-one represents a critical heterocyclic building block within the realm of advanced organic chemistry. As a nitro-substituted pyridone derivative, this compound serves as a versatile precursor for the construction of more complex molecular architectures. Our manufacturing process ensures high consistency and purity, making it an ideal choice for research and development teams focused on pharmaceutical APIs and agrochemical innovations. The unique substitution pattern on the pyridine ring provides chemists with a robust platform for further functionalization.

Manufactured under strict quality control protocols, this intermediate exhibits stable physical properties suitable for various synthetic routes. The presence of both nitro and methyl functional groups allows for diverse chemical transformations, including reduction, substitution, and coupling reactions. We are committed to supplying this material with full traceability and documentation to support your regulatory compliance needs.

Technical Specifications

ParameterValue
CAS Number21901-18-8
Molecular FormulaC6H6N2O3
Molecular Weight154.12
AppearanceOff-white to pale yellow crystalline powder
Assay≥97.0%
Melting Point229-232°C
Density1.36 g/cm³
Boiling Point352.5°C
Flash Point167°C

Chemical Properties and Reactivity

This pyridine derivative is characterized by its thermal stability and specific reactivity profile associated with the nitro group at the third position. The hydroxyl group at the second position contributes to its hydrogen bonding capabilities, influencing solubility in various organic solvents. Researchers utilize these properties to drive specific reaction pathways during multi-step synthesis. The compound is designed to withstand standard laboratory handling conditions while remaining reactive under catalyzed environments.

Industrial Applications

This pyridine derivative is primarily utilized as a key intermediate in the synthesis of fine chemicals. Its specific substitution pattern enables chemists to develop novel compounds with targeted biological activities. Common application areas include pharmaceutical intermediate synthesis for heterocyclic drug candidates, agrochemical research involving pyridine-based herbicides or pesticides, material science applications requiring functionalized nitrogen-containing rings, and custom organic synthesis projects requiring high-purity starting materials.

Quality Assurance and Storage

We prioritize product integrity throughout the supply chain. Each batch undergoes rigorous analytical testing using HPLC and NMR spectroscopy to confirm identity and purity levels. A Certificate of Analysis (COA) is provided with every shipment to ensure compliance with your internal standards. To maintain stability, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. We offer flexible packaging options, including standard 25 kg drums, to accommodate both laboratory-scale trials and large-scale industrial production needs. Our logistics team ensures safe and timely global delivery.