Intermediates

4-Methyl-3-(trifluoromethyl)aniline

  • CAS No.65934-74-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Methyl-3-(trifluoromethyl)aniline intermediate for pharmaceutical and agrochemical synthesis. Available in bulk with full COA.

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Product Technical Details

Product Overview

Our premium grade 4-Methyl-3-(trifluoromethyl)aniline is a specialized fluorinated aromatic amine designed for advanced organic synthesis applications. As a critical building block in the chemical industry, this compound serves as a versatile intermediate for the development of complex pharmaceutical agents and high-performance agrochemical formulations. We understand the stringent requirements of modern chemical manufacturing, which is why our production processes adhere to rigorous quality control standards to ensure consistency and reliability in every batch.

This chemical entity is characterized by its stable aromatic structure and reactive amine group, making it an ideal candidate for nucleophilic substitution and coupling reactions. The presence of the trifluoromethyl group enhances the lipophilicity and metabolic stability of downstream products, which is highly valued in medicinal chemistry and crop protection science. Our facility is equipped with state-of-the-art synthesis and purification technologies to deliver material that meets or exceeds industry specifications.

Technical Specifications

ParameterSpecification
Chemical Name4-Methyl-3-(trifluoromethyl)aniline
CAS Number65934-74-9
Molecular FormulaC8H8F3N
Molecular Weight175.15 g/mol
Purity≥98.0%
AppearanceColorless to light brown crystal
Boiling Point204 °C (lit.)
Density1.220 g/mL at 25 °C
Refractive Index1.49

Industrial Applications

The primary utility of this intermediate lies in its role as a precursor for active pharmaceutical ingredients (APIs) and pesticide active substances. In the pharmaceutical sector, it is utilized in the synthesis of kinase inhibitors and other therapeutic molecules where fluorinated motifs are required to improve bioavailability. In the agrochemical sector, it contributes to the creation of herbicides and fungicides that demand high environmental stability and efficacy. Researchers and process chemists value this material for its reproducibility in scale-up operations.

Quality Assurance and Storage

We maintain a comprehensive quality management system to guarantee the integrity of our products. Each shipment is accompanied by a Certificate of Analysis (COA) detailing critical parameters such as purity, identity, and physical constants. To maintain optimal stability, the product should be stored in tightly closed containers at room temperature, away from direct sunlight and moisture. Proper handling procedures should be followed to ensure safety during transportation and usage in laboratory or industrial settings.

  • Consistent batch-to-batch reproducibility for reliable manufacturing.
  • Available in bulk quantities to support large-scale production needs.
  • Supported by technical documentation and regulatory compliance files.
  • Secure packaging in fiber drums to prevent contamination during transit.