Intermediates

4-[(4-Methyl-1-piperazinyl)methyl]benzoic acid

  • CAS No.106261-48-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4-[(4-Methyl-1-piperazinyl)methyl]benzoic acid (CAS 106261-48-7) designed for pharmaceutical synthesis. Reliable supply for kinase inhibitor production with full documentation.

Request Bulk Pricing

Product Technical Details

Product Overview

4-[(4-Methyl-1-piperazinyl)methyl]benzoic acid is a critical organic building block extensively utilized in the pharmaceutical industry. As a key intermediate, it plays a pivotal role in the synthesis of advanced tyrosine kinase inhibitors. Our manufacturing facility specializes in producing this compound with exceptional purity levels, ensuring it meets the rigorous demands of modern drug development pipelines. We understand the importance of consistency in chemical structure and performance, which is why every batch undergoes strict quality control protocols.

This compound features a benzoic acid backbone substituted with a methylpiperazinyl methyl group, providing unique reactivity profiles suitable for complex coupling reactions. Our production capabilities allow us to scale from laboratory research quantities to large-scale industrial supply, supporting both R&D departments and commercial manufacturing units globally.

Technical Specifications

We adhere to international standards for chemical manufacturing to guarantee product reliability. The following table outlines the typical physical and chemical properties of our standard grade material. Custom specifications are available upon request to align with specific process requirements.

ParameterSpecification
CAS Number106261-48-7
Molecular FormulaC13H18N2O2
Molecular Weight234.29 g/mol
AppearanceWhite crystalline powder
Purity (HPLC)≥99.0%
Density1.175 g/cm3
Boiling Point377.2°C at 760 mmHg
Flash Point181.9°C

Industrial Applications

The primary application of 4-[(4-Methyl-1-piperazinyl)methyl]benzoic acid lies in the pharmaceutical sector, specifically as a precursor for anticancer agents. It is notably used in the synthesis pathway of Imatinib mesylate, a widely recognized therapeutic agent. The high purity of our intermediate ensures minimal impurity carryover into the final active pharmaceutical ingredient (API), facilitating smoother regulatory approval processes.

Beyond oncology, this chemical structure serves as a versatile building block for medicinal chemistry programs focusing on kinase inhibition. Researchers utilize this compound to explore structure-activity relationships (SAR) and develop novel therapeutic candidates. Our technical team provides support to help integrate this material into your existing synthesis routes efficiently.

Quality Assurance and Packaging

Quality is the cornerstone of our operation. Each production lot is accompanied by a comprehensive Certificate of Analysis (COA), detailing test results for identity, purity, and residual solvents. We employ advanced analytical techniques, including HPLC and NMR, to verify chemical structure and composition. Our facility operates under strict safety and environmental guidelines to ensure sustainable production practices.

For packaging, we offer flexible solutions to suit various logistical needs. Standard packing includes 25kg cardboard drums, which are designed to protect the material from moisture and light during transit. Custom packaging configurations are available based on customer specifications. We recommend storing the product in a cool, dry, and well-closed container away from strong oxidizing agents to maintain stability over time.

Global Supply and Support

As a global manufacturer, we are committed to providing reliable supply chains for our international partners. Our logistics network ensures timely delivery to major pharmaceutical hubs worldwide. Whether you require bulk quantities for commercial production or smaller batches for research purposes, we are equipped to meet your demands. Contact our sales team today for detailed pricing, lead times, and technical documentation.