4-(Methylsulfonyl)phenylacetic acid
- CAS No.90536-66-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used primarily in the synthesis of Etoricoxib. Available in bulk with strict quality control and comprehensive documentation.
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Product Overview
4-(Methylsulfonyl)phenylacetic acid is a specialized organic compound serving as a critical building block in modern pharmaceutical synthesis. Characterized by its methylsulfonyl phenyl structure, this chemical exhibits high stability and reactivity suitable for complex multi-step synthesis pathways. Our facility produces this intermediate under stringent quality management systems to ensure consistency across batches. It is particularly valued in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and related therapeutic agents.
We understand the importance of reliability in the supply chain for active pharmaceutical ingredient (API) production. Therefore, every batch undergoes rigorous analytical testing to confirm identity, purity, and physical properties. This commitment allows downstream manufacturers to maintain their own production schedules without interruption due to raw material variability.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 90536-66-6 |
| Molecular Formula | C9H10O4S |
| Molecular Weight | 214.238 g/mol |
| Appearance | White to light yellow crystalline powder |
| Assay (Purity) | ≥96.0% |
| Melting Point | 136-140 °C |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 443.0±37.0 °C at 760 mmHg |
Industrial Applications
The primary application of 4-(Methylsulfonyl)phenylacetic acid lies in its role as a key intermediate for the synthesis of Etoricoxib. Etoricoxib is a well-known selective COX-2 inhibitor used in the management of pain and inflammation. The structural integrity of this acid is crucial for the subsequent coupling and functionalization steps required to build the final active molecule. Impurities at this stage can propagate through the synthesis tree, affecting the yield and quality of the final API.
Beyond Etoricoxib, this compound may serve as a versatile synthon in medicinal chemistry research for developing novel analgesic compounds. Its chemical properties allow for various derivatizations, making it a valuable asset for R&D departments focusing on inflammatory diseases. We support both large-scale commercial production and smaller scale research requirements with flexible packaging options.
Quality Assurance and Packaging
Quality is the cornerstone of our manufacturing process. We employ advanced chromatography and spectroscopy techniques to verify the chemical structure and purity levels. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing all test results against internal and external standards. Our production facilities adhere to good manufacturing practices to minimize contamination risks.
- Stable supply chain ensuring timely delivery for global clients.
- Flexible packaging solutions including 25 kg drums or custom requirements.
- Secure storage recommendations to maintain product integrity during transit.
- Dedicated technical support for synthesis optimization and troubleshooting.
For storage, we recommend keeping the material in a cool, ventilated place away from direct sunlight and moisture. Proper handling ensures the physical appearance and chemical potency remain within specified limits until use. Contact our sales team for detailed safety data sheets and current bulk pricing information tailored to your specific project needs.
