Intermediates

4-Methylthiazole-5-carboxaldehyde

  • CAS No.82294-70-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Methylthiazole-5-carboxaldehyde (CAS 82294-70-0) designed for pharmaceutical intermediate synthesis, ensuring superior reaction efficiency and consistency.

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Product Technical Details

Product Overview

Our premium 4-Methylthiazole-5-carboxaldehyde is a specialized heterocyclic compound engineered for high-performance pharmaceutical synthesis. As a critical building block in medicinal chemistry, this thiazole derivative offers exceptional reactivity and stability, making it an ideal choice for complex organic transformations. We maintain strict manufacturing standards to ensure every batch meets the rigorous demands of modern drug development pipelines.

This chemical features a unique thiazole ring structure substituted with a methyl group and an aldehyde functionality. This specific configuration facilitates various coupling reactions, including condensation and nucleophilic additions, which are essential in constructing advanced therapeutic molecules. Our production process emphasizes purity and consistency, minimizing impurities that could affect downstream reaction yields.

Technical Specifications

ParameterValue
Chemical Name4-Methylthiazole-5-carboxaldehyde
CAS Number82294-70-0
Molecular FormulaC5H5NOS
Molecular Weight127.16 g/mol
AppearanceOff-white to yellow solid
Purity≥99.0%
Melting Point72-78°C
Boiling Point228.1°C
Density1.27 g/cm3
Flash Point91.8°C
Refractive Index1.601

Applications and Usage

This intermediate is primarily utilized in the pharmaceutical industry for the synthesis of advanced cephalosporin antibiotics, including precursors for ceftitoren pivoxil. The aldehyde group serves as a versatile handle for introducing specific side chains required for biological activity. Beyond antibiotic synthesis, this compound finds utility in developing other heterocyclic pharmaceuticals and agrochemicals where thiazole motifs are required for enhanced pharmacokinetic properties.

Researchers value this material for its reliable performance in scale-up processes. Whether used in laboratory-scale discovery or industrial manufacturing, our product ensures reproducible results. The high purity level reduces the need for extensive purification steps post-reaction, thereby optimizing overall production costs and time efficiency.

Quality Assurance and Storage

Quality is the cornerstone of our manufacturing philosophy. Each batch of 4-Methylthiazole-5-carboxaldehyde undergoes comprehensive analytical testing, including HPLC and GC analysis, to verify purity and identity. We provide a Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with international quality standards.

  • Strict quality control protocols at every production stage
  • Advanced analytical verification for consistency
  • Secure packaging to prevent moisture and light exposure
  • Global logistics support for timely delivery

For optimal stability, store this product in a cool, ventilated area away from direct sunlight and heat sources. Keep containers tightly closed when not in use to prevent oxidation or moisture absorption. Proper handling procedures, including the use of appropriate personal protective equipment (PPE), are recommended during transfer and processing to ensure safety in the workplace.