Intermediates

4-Nitrobenzotrifluoride

  • CAS No.402-54-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Nitrobenzotrifluoride (CAS 402-54-0) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical manufacturing processes.

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Product Technical Details

Product Overview

4-Nitrobenzotrifluoride is a premier fluorinated aromatic compound widely recognized for its stability and versatility in complex chemical transformations. As a critical building block in modern organic synthesis, this substance serves as an essential precursor for the development of pharmaceuticals, agrochemicals, and advanced materials. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for research laboratories and large-scale industrial production facilities alike.

The presence of both the nitro group and the trifluoromethyl moiety provides unique reactivity profiles, allowing chemists to perform selective reductions, nucleophilic substitutions, and cross-coupling reactions with high efficiency. This dual functionality makes it a valuable asset in the synthesis of bioactive molecules where fluorine incorporation is required to enhance metabolic stability and bioavailability.

Key Specifications

We adhere to strict quality control protocols to guarantee consistency across every batch. The following technical parameters define the standard grade available for immediate shipment:

ParameterSpecification
Chemical Name4-Nitrobenzotrifluoride
CAS Number402-54-0
Molecular FormulaC7H4F3NO2
Molecular Weight191.107 g/mol
AppearanceYellow crystalline powder
Assay (Purity)≥98.0%
Melting Point38-40 °C
Boiling Point207.6 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point88.3 °C

Industrial Applications

This fluorinated intermediate is extensively utilized in the preparation of various downstream products. In the pharmaceutical sector, it acts as a key starting material for constructing trifluoromethylated aromatic structures found in numerous therapeutic agents. The electron-withdrawing nature of the nitro group facilitates reduction to the corresponding aniline, which can then be further derivatized into amides, ureas, or heterocycles.

Additionally, the compound finds application in the agrochemical industry for synthesizing herbicides and pesticides that require high environmental stability. Materials science researchers also leverage this chemical to develop polymers with enhanced thermal and chemical resistance properties. Our global supply chain supports diverse manufacturing needs, ensuring timely delivery for critical project timelines.

Quality Assurance and Storage

Every production lot undergoes rigorous analytical testing, including HPLC and GC analysis, to verify compliance with stated specifications. A Certificate of Analysis (COA) is provided with each shipment to document quality metrics. To maintain optimal integrity, the product should be stored in a cool, ventilated area away from direct sunlight and incompatible materials.

Packaging is available in standard 25 kg drums, with customization options to suit specific logistical requirements. We prioritize safety and compliance, ensuring all handling guidelines are clearly communicated to our partners. For technical inquiries or bulk pricing requests, our expert team is ready to assist with detailed synthesis routes and application support.