4-Nitroisoindolin-1-one
- CAS No.366452-97-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Nitroisoindolin-1-one (CAS 366452-97-3) designed for pharmaceutical synthesis, specifically as a key intermediate for Lenalidomide production.
Request Bulk PricingProduct Technical Details
Product Overview
4-Nitroisoindolin-1-one is a specialized organic compound widely recognized within the pharmaceutical industry for its critical role in complex synthesis pathways. As a high-value chemical building block, this substance serves as an essential precursor in the manufacturing of advanced therapeutic agents. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream pharmaceutical applications.
The compound is characterized by its stable chemical structure and high reactivity profile, making it ideal for multi-step organic synthesis processes. We understand the stringent requirements of modern drug development, which is why our production lines are optimized to deliver material that meets or exceeds international pharmacopeia standards. Each batch undergoes rigorous analytical testing to verify identity, purity, and physical properties.
Technical Specifications
To support our partners in research and development, we provide comprehensive technical data for every shipment. The following table outlines the key physical and chemical parameters associated with this product. Our quality assurance team verifies these specifications using advanced instrumentation including HPLC, NMR, and mass spectrometry.
| Parameter | Specification |
|---|---|
| CAS Number | 366452-97-3 |
| Molecular Formula | C8H6N2O3 |
| Molecular Weight | 178.15 g/mol |
| Appearance | White to light yellow powder |
| Assay (Purity) | ≥98.0% |
| Density | 1.45 g/cm3 |
| Boiling Point | 488.773°C at 760 mmHg |
| Flash Point | 249.401°C |
| Refractive Index | 1.632 |
Industrial Applications
The primary application of 4-Nitroisoindolin-1-one lies in the synthesis of immunomodulatory pharmaceutical agents. Specifically, it acts as a crucial intermediate in the production pipeline for Lenalidomide, a medication used in the treatment of various hematological conditions. The integrity of this intermediate directly influences the yield and purity of the final active pharmaceutical ingredient (API).
Beyond its specific use in immunomodulatory therapies, this nitro-substituted isoindolinone derivative is valuable in medicinal chemistry research. It serves as a versatile scaffold for developing novel heterocyclic compounds. Our clients utilize this material for process development, scale-up studies, and commercial manufacturing of finished dosage forms. We support both laboratory-scale research quantities and large-scale industrial production needs.
Quality Assurance and Safety
Safety and compliance are paramount in our operations. We adhere to global safety standards for the handling and storage of fine chemicals. The product should be stored in a cool, ventilated area away from incompatible substances. Proper personal protective equipment (PPE) is recommended during handling to prevent inhalation or skin contact.
Our commitment to quality extends beyond the product itself. We provide full documentation with every order, including Certificates of Analysis (COA), Method Validation Reports, and Safety Data Sheets (SDS). Our logistics network ensures secure packaging, typically in 25 kg drums, with customization available based on specific customer requirements. By choosing our facility, you gain a partner dedicated to supply chain stability and chemical excellence.
